Ovarian mucinous cystadenocarcinoma
Updates to Article Attributes
Mucinous cystadenocarcinoma of the ovary is a rare malignant ovarian mucinous tumour. This type can account for 5-10% of all ovarian mucinous tumours. It is a type of ovarian epithelial tumour.
Pathology
Retrospective studies have suggested that many mucinous carcinomas initially diagnosed as primary to the ovary have in fact metastasised from another site 4.
Associations
- a development of mucinous cystadenocarcinoma has been very rarely associated with malignant transformation of a mature cystic teratoma 1
Radiographic features
In general, the cell type (e.g. serous, mucinous) often cannot be determined on the basis of appearance at MR imaging, CT, or ultrasound 6. Biopsy or excision is necessary.
A mucinous ovarian carcinoma is less likely to be bilateral than serous carcinoma, with bilateral lesions occurring in 5-10% of the stage I cases.
General
Mucinous tumors are typically multilocular, with numerous smooth, thin-walled cysts. Mucoid material is found within the cysts, sometimes accompanied by haemorrhagic or cellular debris. A proportionately greater solid, nonfatty, non-fibrous tissue is often considered the most powerful predictor of malignancy 6.
Ultrasound
- appearance is similar to an ovarian mucinous cystadenoma, but with mural thickening, solid components, or aggressive features.
CT
CT may demonstrate high attenuation in some loculi due to the high protein content of the mucoid material
MRI
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T1
- the signal intensity of mucin on T1-weighted images varies depending on the degree of mucin concentration
- on T1-weighted images, loculi with watery mucin have a lower signal intensity than loculi with thicker mucin
.
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T2
- on T2-weighted images, the corresponding signal intensities are flipped, so that loculi with watery mucin have a high signal intensity and loculi with thicker mucin appear slightly hypointense
.
- on T2-weighted images, the corresponding signal intensities are flipped, so that loculi with watery mucin have a high signal intensity and loculi with thicker mucin appear slightly hypointense
Staging
The staging is the same as general ovarian cancer staging.
Treatment and prognosis
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See also
-<p><strong>Mucinous cystadenocarcinoma of the ovary </strong>is a rare malignant <a href="/articles/ovarian-mucinous-tumours">ovarian mucinous tumour</a>. This type can account for 5-10% of all ovarian mucinous tumours. It is a type of <a title="Ovarian epithelial tumours" href="/articles/epithelial-ovarian-tumours">ovarian epithelial tumour</a>. </p><h4>Pathology</h4><p>Retrospective studies have suggested that many mucinous carcinomas initially diagnosed as primary to the ovary have in fact metastasised from another site <sup>4</sup>.</p><h5>Associations</h5><ul><li>a development of mucinous cystadenocarcinoma has been very rarely associated with malignant transformation of a <a href="/articles/mature-cystic-ovarian-teratoma">mature cystic teratoma</a> <sup>1</sup>- +<p><strong>Mucinous cystadenocarcinoma of the ovary </strong>is a rare malignant <a href="/articles/ovarian-mucinous-tumours">ovarian mucinous tumour</a>. This type can account for 5-10% of all ovarian mucinous tumours. It is a type of <a href="/articles/epithelial-ovarian-tumours">ovarian epithelial tumour</a>. </p><h4>Pathology</h4><p>Retrospective studies have suggested that many mucinous carcinomas initially diagnosed as primary to the ovary have in fact metastasised from another site <sup>4</sup>.</p><h5>Associations</h5><ul><li>a development of mucinous cystadenocarcinoma has been very rarely associated with malignant transformation of a <a href="/articles/mature-cystic-ovarian-teratoma-1">mature cystic teratoma</a> <sup>1</sup>
-<li>on T1-weighted images, loculi with watery mucin have a lower signal intensity than loculi with thicker mucin. </li>- +<li>on T1-weighted images, loculi with watery mucin have a lower signal intensity than loculi with thicker mucin</li>
-<strong>T2</strong><ul><li>on T2-weighted images, the corresponding signal intensities are flipped, so that loculi with watery mucin have high signal intensity and loculi with thicker mucin appear slightly hypointense.</li></ul>- +<strong>T2</strong><ul><li>on T2-weighted images, the corresponding signal intensities are flipped, so that loculi with watery mucin have a high signal intensity and loculi with thicker mucin appear slightly hypointense</li></ul>
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