Pseudoenhancement

Changed by Matt A. Morgan, 6 Dec 2015

Updates to Article Attributes

Title was changed:
CT Pseudoenhancement artifact of Renal Cyst
Status changed from pending review to published (public).
Published At was set to .
Body was changed:

CT PseudoenhancementPseudoenhancement is an artifact in postcontrast CT evaluation of  Renal Cystrenal cysts.

A renal cystic lesion is considered "enhancing" when there is at least a False Increase20 HU increase in attenuation from the precontrast series to the postcontrast series. An increase in attenuation of renal cyst10-20 HU is considered indeterminate.

Caution must be exercised, however, when using this criteria in post contrast CT scan study comparing with non-contrast study due to beam hardening artifact caused by increased contrast backgroundsmall (<1 cm) intraparenchymal renal cystic lesions. These small lesions may actually be water attenuation.

The smaller (<10 HU), but because of the cyst sizeintense enhancement of the more likely to have more pseudo enhancement particularly less than 2cm diameter.

10 HU or lesssurrounding renal parenchyma, the Hounsfield unit reconstruction algorithm may artificially increase  inthe attenuation is acceptablein the benign cyst, making it appear as a possibly malignant enhancing cystic lesion.

10 – 20 HU increase is indeterminate and additional imaging evaluation may be recommended.

>20 HU almost considered true abnormal enhancement .

  • -<p><strong>CT Pseudoenhancement artifact of  Renal Cyst is a </strong><strong>False Increase in attenuation of renal cyst in post contrast CT scan study comparing with non-contrast study due to beam hardening artifact caused by increased contrast background attenuation.</strong></p><p><strong>The smaller the cyst size the more likely to have more pseudo enhancement particularly less than 2cm diameter.</strong></p><p><strong>10 HU or less increase  in attenuation is acceptable.</strong></p><p><strong>10 – 20 HU increase is indeterminate and additional imaging evaluation may be recommended.</strong></p><p><strong>&gt;20 HU almost considered true abnormal enhancement .</strong></p>
  • +<p><strong>Pseudoenhancement </strong>is an artifact in postcontrast CT evaluation of renal cysts.</p><p>A renal cystic lesion is considered "enhancing" when there is at least a 20 HU increase in attenuation from the precontrast series to the postcontrast series. An increase in attenuation of 10-20 HU is considered indeterminate.</p><p>Caution must be exercised, however, when using this criteria in small (&lt;1 cm) intraparenchymal renal cystic lesions. These small lesions may actually be water attenuation (&lt;10 HU), but because of the intense enhancement of the surrounding renal parenchyma, the Hounsfield unit reconstruction algorithm may artificially increase the attenuation in the benign cyst, making it appear as a possibly malignant enhancing cystic lesion.</p>

References changed:

  • 1. Coulam CH, Sheafor DH, Leder RA et-al. Evaluation of pseudoenhancement of renal cysts during contrast-enhanced CT. AJR Am J Roentgenol. 2000;174 (2): 493-8. <a href="http://dx.doi.org/10.2214/ajr.174.2.1740493">doi:10.2214/ajr.174.2.1740493</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/10658730">Pubmed citation</a><span class="auto"></span>
  • 2. Maki DD, Birnbaum BA, Chakraborty DP et-al. Renal cyst pseudoenhancement: beam-hardening effects on CT numbers. Radiology. 1999;213 (2): 468-72. <a href="http://dx.doi.org/10.1148/radiology.213.2.r99nv33468">doi:10.1148/radiology.213.2.r99nv33468</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/10551228">Pubmed citation</a><span class="auto"></span>
  • Coulam CH, Sheafor DH, Leder RA et-al. Evaluation of pseudoenhancement of renal cysts during contrast-enhanced CT. AJR Am J Roentgenol. 2000;174 (2): 493-8. <a href="http://dx.doi.org/10.2214/ajr.174.2.1740493">doi:10.2214/ajr.174.2.1740493</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/10658730">Pubmed citation</a><span class="auto"></span>
  • Maki DD, Birnbaum BA, Chakraborty DP et-al. Renal cyst pseudoenhancement: beam-hardening effects on CT numbers. Radiology. 1999;213 (2): 468-72. <a href="http://dx.doi.org/10.1148/radiology.213.2.r99nv33468">doi:10.1148/radiology.213.2.r99nv33468</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/10551228">Pubmed citation</a><span class="auto"></span>

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