Pseudogestational sac

Changed by Matt A. Morgan, 29 Dec 2014

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PseudogestationalPseudo-gestational sac

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Pseudo-gestationalPseudogestational sac
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APseudo-gestational pseudogestational sac is only important as it can be erroneously interpreted as is the idea that a true gestational sac. This is especially dangerous ifsmall amount of intrauterine fluid in the setting of a positive pregnancy test and abdominal pain, if an  could be erroneously interpreted as a true gestational sac in ectopic pregnancy.

The sign was originally reported before the use of endovaginal ultrasound imaging and caution should be exercised if considering diagnosing a pseudogestational sac with modern ultrasound equipment. In a woman with a postive beta-hCG, any intrauterine sac-like fluid collection seen on ultrasound is highly likely to be excluded as a result of what is thought to be an intrauterine pregnancy.

Typically a pseudo-gestationalgestational sac is simply a small focal accumulation of fluid within the uterine cavity6.

Radiographic features

Ultrasound
  • often seen asgenerally irregularly-shaped with pointed edges and/or filled with debris
  • centrally located, rather than eccentrically located
  • does not demonstrate ayolk sac
  • a double decidual layer is compatible with intrauterine fluid collectionpregnancy, but lack of this sign is not specific for pseudogestational sac
    • may be surrounded by a singlethick decidual layer5
  • it is typically located centrally, does not demonstrate a yolk sac and does not have a double decidual sign.

It should be distinguished from an intra-decidual sign, which is also a sign of an early pregnancy.

The idea of beta-hCG "discriminatory levels" has also undergone revision since this sign was formulated. Caution should be exercised in making a diagnosis of pseudogestational sac because an intrauterine fluid collection does not show a yolk sac at a beta-HCG level >2000 7. Therapy should not be initiated in a hemodynamically stable woman on the basis of a single beta-hCG level.

  • -<p><strong>Pseudo-gestational sac</strong> is only important as it can be erroneously interpreted as a true <a href="/articles/gestational-sac">gestational sac</a>. This is especially dangerous if in the setting of positive pregnancy test and abdominal pain, if an <a href="/articles/ectopic-pregnancy">ectopic pregnancy</a> is to be excluded as a result of what is thought to be an intrauterine pregnancy.</p><p>Typically a pseudo-gestational sac is simply a small focal accumulation of fluid within the uterine cavity. </p><h4>Radiographic features</h4><h5>Ultrasound</h5><ul>
  • -<li>often seen as a intrauterine fluid collection surrounded by a single decidual layer <sup>5</sup>
  • +<p>A<strong> pseudogestational sac</strong> is the idea that a small amount of intrauterine fluid in the setting of a positive pregnancy test and abdominal pain could be erroneously interpreted as a true <a href="/articles/gestational-sac">gestational sac</a> in <a href="/articles/ectopic-pregnancy">ectopic pregnancy</a>.</p><p>The sign was originally reported before the use of endovaginal ultrasound imaging and caution should be exercised if considering diagnosing a pseudogestational sac with modern ultrasound equipment. In a woman with a postive beta-hCG, any intrauterine sac-like fluid collection seen on ultrasound is highly likely to be a gestational sac <sup>6</sup>.</p><h4>Radiographic features</h4><h5>Ultrasound</h5><ul>
  • +<li>generally irregularly-shaped with pointed edges and/or filled with debris</li>
  • +<li>centrally located, rather than eccentrically located</li>
  • +<li>does not demonstrate a <a href="/articles/yolk-sac">yolk sac</a>
  • -<li>it is typically located centrally, does not demonstrate a <a href="/articles/yolk-sac">yolk sac</a> and does not have a <a href="/articles/double-decidual-sac-sign-1">double decidual sign</a>.</li>
  • -</ul><p>It should be distinguished from an <a href="/articles/intra-decidual-sac-sign">intra-decidual sign</a>, which is also a sign of an <a href="/articles/early-pregnancy">early pregnancy</a>.</p>
  • +<li>a <a title="Double decidual sac sign (DDDS)" href="/articles/double-decidual-sac-sign-1">double decidual layer</a> is compatible with intrauterine pregnancy, but lack of this sign is not specific for pseudogestational sac<ul><li>may be surrounded by a thick decidual layer</li></ul>
  • +</li>
  • +</ul><p>It should be distinguished from an <a href="/articles/intradecidual-sac-sign-1">intra-decidual sign</a>, which is also a sign of an <a href="/articles/early-pregnancy">early pregnancy</a>.</p><p>The idea of beta-hCG "discriminatory levels" has also undergone revision since this sign was formulated. Caution should be exercised in making a diagnosis of pseudogestational sac because an intrauterine fluid collection does not show a yolk sac at a beta-HCG level &gt;2000 <sup>7</sup>. Therapy should not be initiated in a hemodynamically stable woman on the basis of a single beta-hCG level.</p>

References changed:

  • 6. Doubilet PM. Ultrasound Evaluation of the First Trimester. Radiol. Clin. North Am. 2014;52 (6): 1191-1199. <a href="http://dx.doi.org/10.1016/j.rcl.2014.07.004">doi:10.1016/j.rcl.2014.07.004</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/25444100">Pubmed citation</a><span class="auto"></span>
  • 7. Doubilet PM, Benson CB. Further evidence against the reliability of the human chorionic gonadotropin discriminatory level. J Ultrasound Med. 2012;30 (12): 1637-42. <a href="http://www.ncbi.nlm.nih.gov/pubmed/22123998">Pubmed citation</a><span class="auto"></span>

Tags changed:

  • abr certifying ultrasound

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