Rai staging system for chronic lymphoid leukemia
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The Rai staging system is one of the two staging systems currently adopted in assesmentassessment of chronic lymphocytic leukaemia (CLL).
It comprises of stages 0 to IV and classifies chronic lymphocytic leukemia into low, intermediate and high-risk categories, which correspond with stages 0, I & II, and III & IV, respectively:
-
Rai stage 0:
:- low risk
-
lymphocytosis: a high lymphocyte count defined as more than 15,000 lymphocytes per cubic millimeter (> 15,000
/ mm/mm3).
-
Rai stage I:
:- intermediate risk
- lymphocytosis + lymphadenopathy.
-
Rai stage II:
:- patients are also intermediate risk
- lymphocytosis plus an enlarged liver (hepatomegaly) or enlarged spleen (splenomegaly), with or without lymphadenopathy
.
-
Rai stage III:
:- patients are high-risk
- lymphocytosis plus anaemia with or without lymphadenopathy, hepatomegaly, or splenomegaly
.
-
Rai stage IV:
:- high-risk
- lymphocytosis + thrombocytopenia (< 100
- 103-103 /dL).
See also
-<p>The <strong>Rai staging system</strong> is one of the two staging systems currently adopted in assesment of <a href="/articles/chronic-lymphocytic-leukaemia" title="chronic lymphocytic leukaemia ">chronic lymphocytic leukaemia </a>(<a href="/articles/cll" title="CLL">CLL</a>). </p><p>It comprises of stages 0 to IV and classifies chronic lymphocytic leukemia into low, intermediate and high-risk categories, which correspond with stages 0, I & II, and III & IV, respectively : </p><ul>- +<p>The <strong>Rai staging system</strong> is one of the two staging systems currently adopted in assessment of <a href="/articles/chronic-lymphocytic-leukaemia">chronic lymphocytic leukaemia </a>(<a href="/articles/cll">CLL</a>).</p><p>It comprises of stages 0 to IV and classifies chronic lymphocytic leukemia into low, intermediate and high-risk categories, which correspond with stages 0, I & II, and III & IV, respectively:</p><ul>
-<strong>Rai stage 0</strong> :-<ul>- +<strong>Rai stage 0:</strong><ul>
-<a href="/articles/lymphocytosis" title="lymphocytosis">lymphocytosis</a> : a high lymphocyte count defined as more than 15,000 lymphocytes per cubic millimeter (> 15,000 / mm<sup>3</sup>). </li>- +<a href="/articles/lymphocytosis">lymphocytosis</a>: a high lymphocyte count defined as more than 15,000 lymphocytes per cubic millimeter (> 15,000/mm<sup>3</sup>)</li>
-<strong>Rai stage I</strong> :-<ul>- +<strong>Rai stage I:</strong><ul>
-<li>lymphocytosis + <a href="/articles/lymph-node-enlargement" title="Lymphadenopathy">lymphadenopathy</a>. </li>- +<li>lymphocytosis + <a href="/articles/lymph-node-enlargement">lymphadenopathy</a>.</li>
-<strong>Rai stage II</strong> :-<ul>- +<strong>Rai stage II:</strong><ul>
-<li>lymphocytosis plus an <strong>enlarged liver</strong> (<a href="/articles/hepatomegaly" title="Hepatomegaly">hepatomegaly</a>) or <strong>enlarged spleen</strong> (<a href="/articles/splenomegaly" title="Splenomegaly">splenomegaly</a>), with or without lymphadenopathy.</li>- +<li>lymphocytosis plus an enlarged liver (<a href="/articles/hepatomegaly">hepatomegaly</a>) or enlarged spleen (<a href="/articles/splenomegaly">splenomegaly</a>), with or without lymphadenopathy</li>
-<strong>Rai stage III</strong> :-<ul>- +<strong>Rai stage III:</strong><ul>
-<li>lymphocytosis plus <strong>anaemia</strong> with or without lymphadenopathy, hepatomegaly, or splenomegaly. </li>- +<li>lymphocytosis plus anaemia with or without lymphadenopathy, hepatomegaly, or splenomegaly</li>
-<strong>Rai stage IV</strong> :-<ul>- +<strong>Rai stage IV:</strong><ul>
-<li>lymphocytosis + <strong>thrombocytopenia</strong> (< 100 - 103 /dL). </li>- +<li>lymphocytosis + thrombocytopenia (< 100-103 /dL)</li>
-</ul><h4>See also</h4><ul><li><a href="/articles/binet-staging-system-for-chronic-lymphocytic-leukaemia" title="Binet staging for CLL">Binet staging system of chronic lymphoid leukaemia</a></li></ul>- +</ul><h4>See also</h4><ul><li><a href="/articles/binet-staging-system-for-chronic-lymphocytic-leukaemia">Binet staging system of chronic lymphoid leukaemia</a></li></ul>
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