Reye syndrome
Disclosures
- updated 15 Jul 2022:
Nothing to disclose
Updates to Article Attributes
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Reye syndrome is a rare paediatric condition characterised by acute onset encephalopathy, severe vomiting and fatty liver failure. It typically presents in children recovering from a viral illness, most commonly influenza or chickenpox 1.
Epidemiology
Reye syndrome is usually seen between the ages of 5 and 14 2.
Associations
The disease is very strongly associated with recent salicylate therapy. For this reason, administration of aspirin to children is usually contraindicated, and reserved only for specific scenarios 3.
Treatment and prognosis
Treatment is supportive, often involving ITUICU care. Mortality from Reye syndrome is 20-40%.
History and etymology
The disease was first described by the Australian pathologist Ralph Douglas Kenneth Reye in 1963 2.
-<p><strong>Reye syndrome </strong>is a rare paediatric condition characterised by acute onset encephalopathy, severe vomiting and fatty liver failure. It typically presents in children recovering from a viral illness, most commonly influenza or chickenpox <sup>1</sup>. </p><h4>Epidemiology</h4><p>Reye syndrome is usually seen between the ages of 5 and 14 <sup>2</sup>. </p><h5>Associations</h5><p>The disease is very strongly associated with recent salicylate therapy. For this reason, administration of aspirin to children is usually contraindicated, and reserved only for specific scenarios <sup>3</sup>. </p><h4>Treatment and prognosis</h4><p>Treatment is supportive, often involving ITU care. Mortality from Reye syndrome is 20-40%. </p><h4>History and etymology</h4><p>The disease was first described by the Australian pathologist Ralph Douglas Kenneth Reye <sup>2</sup>. </p><p> </p>- +<p><strong>Reye syndrome </strong>is a rare paediatric condition characterised by acute onset encephalopathy, severe vomiting and fatty liver failure. It typically presents in children recovering from a viral illness, most commonly influenza or chickenpox <sup>1</sup>. </p><h4>Epidemiology</h4><p>Reye syndrome is usually seen between the ages of 5 and 14 <sup>2</sup>. </p><h5>Associations</h5><p>The disease is very strongly associated with recent salicylate therapy. For this reason, administration of aspirin to children is usually contraindicated, and reserved only for specific scenarios <sup>3</sup>. </p><h4>Treatment and prognosis</h4><p>Treatment is supportive, often involving ICU care. Mortality from Reye syndrome is 20-40%. </p><h4>History and etymology</h4><p>The disease was first described by the Australian pathologist <strong>Ralph Douglas Kenneth Reye</strong> in 1963 <sup>2</sup>. </p><p> </p>
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