Spermatic cord liposarcoma
Updates to Article Attributes
Spermatic cord liposarcomaliposarcomas isare the most common malignant tumortumour of the spermatic cord. Most present as painless, slow-growing masses and can be mistaken for inguinal hernias. They are usually well-differentiated and spread by local extension.
Epidemiology
In a large population-based registry, the annual incidence of spermatic cord tumortumour (SCT) is 0.3 cases/million3.
Clinical presentation
Most present as painless, slow-growing masses. They can be mistaken for an inguinal hernia, hydrocele, or other paratesticular tumours.
Pathology
Most are low-grade and well-differentiated and spread by local extension. High-grade tumours can spread via hematogenous or lymphatic routes 3.
In a large population-based registry 362 patients with SCT were identified, with histological subtypes of liposarcoma (46%), leiomyosarcoma (20%), histiocytoma (13%), and rhabdomyosarcoma (9%)3.
Clinical presentation
Most present as painless, slow growing masses. They can be mistaken for inguinal hernia, hydrocele, or other paratesticular neoplasms.
Pathology
Most are low-grade and well-differentiated, and spread by local extension. High-grade tumors can can spread via hematogenous or lymphatic routes3.
Radiographic features
CT and MRI provide greater characterization and staging information than ultrasound. Fat They appear as a fat-containing tumortumour with variable amounts of soft tissue, nodularity, and septations.
Treatment and prognosis
Standard surgical treatment includes high orchiectomy and resection of the tumortumour and spermatic cord. Lymph node dissection is occasionally performed. Chemotherapy and radiation therapy depend on the tumortumour grade, stage, and risk of recurrence1.
Differential diagnosis
Lipoma is the most common benign tumortumour of the spermatic cord, and much more common than liposarcoma (45% of paratesticular masses)3. Other malignant tumorstumours of the spermatic cord include leiomyosarcoma, histiocytoma, and rhabdomyosarcoma.
See also
-<p><strong>Spermatic cord liposarcoma </strong>is the most common malignant tumor of the spermatic cord. Most present as painless, slow-growing masses and can be mistaken for inguinal hernias. They are usually well-differentiated and spread by local extension. </p><h4>Epidemiology</h4><p>In a large population-based registry, the annual incidence of spermatic cord tumor (SCT) is 0.3 cases/million. 362 patients with SCT were identified, with histological subtypes of liposarcoma (46%), leiomyosarcoma (20%), histiocytoma (13%), and rhabdomyosarcoma (9%)<sup>3</sup>. </p><h4>Clinical presentation</h4><p>Most present as painless, slow growing masses. They can be mistaken for inguinal hernia, hydrocele, or other paratesticular neoplasms. </p><h4>Pathology</h4><p>Most are low-grade and well-differentiated, and spread by local extension. High-grade tumors can can spread via hematogenous or lymphatic routes<sup>3</sup>. </p><h4>Radiographic features</h4><p>CT and MRI provide greater characterization and staging information than ultrasound. Fat-containing tumor with variable amounts of soft tissue, nodularity, and septations. </p><h4>Treatment and prognosis</h4><p>Standard surgical treatment includes high orchiectomy and resection of the tumor and spermatic cord. Lymph node dissection is occasionally performed. Chemotherapy and radiation therapy depend the tumor grade, stage, and risk of recurrence<sup>1</sup>. </p><h4>Differential diagnosis</h4><p>Lipoma is the most common benign tumor of the spermatic cord, and much more common than liposarcoma (45% of paratesticular masses)<sup>3</sup>. Other malignant tumors of the spermatic cord include leiomyosarcoma, histiocytoma, and rhabdomyosarcoma. </p><h4>See also</h4><p><a href="/articles/paratesticular-lesions">Paratesticular lesions</a></p>- +<p><strong>Spermatic cord liposarcomas </strong>are the most common malignant tumour of the <a title="Spermatic cord" href="/articles/spermatic-cord">spermatic cord</a>. Most present as painless, slow-growing masses and can be mistaken for <a title="Inguinal hernias" href="/articles/inguinal-hernia">inguinal hernias</a>. They are usually well-differentiated and spread by local extension. </p><h4>Epidemiology</h4><p>In a large population-based registry, the annual incidence of spermatic cord tumour (SCT) is 0.3 cases/million <sup>3</sup>.</p><h4>Clinical presentation</h4><p>Most present as painless, slow-growing masses. They can be mistaken for an inguinal hernia, <a title="Hydrocele" href="/articles/hydrocoele-1">hydrocele</a>, or other <a title="Paratesticular tumours" href="/articles/paratesticular-tumours-1">paratesticular tumours</a>. </p><h4>Pathology</h4><p>Most are low-grade and well-differentiated and spread by local extension. High-grade tumours can spread via hematogenous or lymphatic routes <sup>3</sup>. </p><p>In a large population-based registry 362 patients with SCT were identified, with histological subtypes of liposarcoma (46%), leiomyosarcoma (20%), histiocytoma (13%), and rhabdomyosarcoma (9%) <sup>3</sup>. </p><h4>Radiographic features</h4><p>CT and MRI provide greater characterization and staging information than ultrasound. They appear as a fat-containing tumour with variable amounts of soft tissue, nodularity, and septations. </p><h4>Treatment and prognosis</h4><p>Standard surgical treatment includes high orchiectomy and resection of the tumour and spermatic cord. Lymph node dissection is occasionally performed. Chemotherapy and radiation therapy depend on the tumour grade, stage, and risk of recurrence<sup>1</sup>. </p><h4>Differential diagnosis</h4><p>Lipoma is the most common benign tumour of the spermatic cord, and much more common than liposarcoma (45% of paratesticular masses)<sup>3</sup>. Other malignant tumours of the spermatic cord include leiomyosarcoma, histiocytoma, and rhabdomyosarcoma. </p><h4>See also</h4><ul><li><a href="/articles/paratesticular-lesions">paratesticular lesions</a></li></ul>
References changed:
- 1. Yamamichi G, Nakata W, Yamamoto A, Tsujimura G, Tsujimoto Y, Nin M, Tsujihata M. Liposarcoma of the spermatic cord associated with scrotum lipoma: A case report and review of the literature. (2018) Urology case reports. 17: 114-116. <a href="https://doi.org/10.1016/j.eucr.2018.01.022">doi:10.1016/j.eucr.2018.01.022</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/29541595">Pubmed</a> <span class="ref_v4"></span>
- 2. Rodríguez D, Barrisford GW, Sanchez A et-al. Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes. Urol. Oncol. 2014;32 (1): 52.e19-25. doi:10.1016/j.urolonc.2013.08.009 - Pubmed citation
- 3. Akbar SA, Sayyed TA, Jafri SZ, Hasteh F, Neill JS. Multimodality imaging of paratesticular neoplasms and their rare mimics. (2003) Radiographics : a review publication of the Radiological Society of North America, Inc. 23 (6): 1461-76. <a href="https://doi.org/10.1148/rg.236025174">doi:10.1148/rg.236025174</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/14615558">Pubmed</a> <span class="ref_v4"></span>
- 4. Woodward PJ, Schwab CM, Sesterhenn IA. From the archives of the AFIP: extratesticular scrotal masses: radiologic-pathologic correlation. (2003) Radiographics : a review publication of the Radiological Society of North America, Inc. 23 (1): 215-40. <a href="https://doi.org/10.1148/rg.231025133">doi:10.1148/rg.231025133</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/12533657">Pubmed</a> <span class="ref_v4"></span>
- Yamamichi G, Nakata W, Yamamoto A, Tsujimura G, Tsujimoto Y, Nin M, Tsujihata M. Liposarcoma of the spermatic cord associated with scrotum lipoma: A case report and review of the literature. (2018) Urology case reports. 17: 114-116. <a href="https://doi.org/10.1016/j.eucr.2018.01.022">doi:10.1016/j.eucr.2018.01.022</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/29541595">Pubmed</a> <span class="ref_v4"></span>
- Rodríguez D, Barrisford GW, Sanchez A et-al. Primary spermatic cord tumors: disease characteristics, prognostic factors, and treatment outcomes. Urol. Oncol. 2014;32 (1): 52.e19-25. doi:10.1016/j.urolonc.2013.08.009 - Pubmed citation
- Akbar SA, Sayyed TA, Jafri SZ, Hasteh F, Neill JS. Multimodality imaging of paratesticular neoplasms and their rare mimics. (2003) Radiographics : a review publication of the Radiological Society of North America, Inc. 23 (6): 1461-76. <a href="https://doi.org/10.1148/rg.236025174">doi:10.1148/rg.236025174</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/14615558">Pubmed</a> <span class="ref_v4"></span>
- Woodward PJ, Schwab CM, Sesterhenn IA. From the archives of the AFIP: extratesticular scrotal masses: radiologic-pathologic correlation. (2003) Radiographics : a review publication of the Radiological Society of North America, Inc. 23 (1): 215-40. <a href="https://doi.org/10.1148/rg.231025133">doi:10.1148/rg.231025133</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/12533657">Pubmed</a> <span class="ref_v4"></span>
Tags changed:
- cases
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- Oncology
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