Stauffer syndrome
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Stauffer syndrome describesis paraneoplastic nephrogenic hepatomegaly.
It involves a renal malignancy (mostmost commonly occurs in the setting of renal cell carcinoma), and is the enlargement the liver without evidence of hepatic or splenic metastases, but organomegaly of one or both, and deranged liver functionmetastases.
It It is a cause of cholestasis, and cholestatic jaundice.
It is a form of paraneoplastic disease.
History and etymology
It is named afterMaurice H. Stauffer, American gastroenterologist who first described it in 1961.
-<p><strong>Stauffer syndrome</strong> describes nephrogenic hepatomegaly.</p><p>It involves a renal malignancy (most commonly <a href="/articles/renal-cell-carcinoma-1">renal cell carcinoma</a>) without evidence of hepatic or splenic metastases, but organomegaly of one or both, and deranged liver function.</p><p>It is a cause of cholestasis, and cholestatic <a href="/articles/jaundice">jaundice</a>. </p><p>It is a form of paraneoplastic disease.</p><h4>History and etymology</h4><p>It is named after <strong>Maurice H. Stauffer</strong>, American gastroenterologist who first described it in 1961.</p>- +<p><strong>Stauffer syndrome</strong> is <a title="Paraneoplastic syndrome" href="/articles/paraneoplastic-syndromes">paraneoplastic</a> nephrogenic <a title="Hepatomegaly" href="/articles/hepatomegaly">hepatomegaly</a>. It most commonly occurs in the setting of <a title="Renal cell carcinoma" href="/articles/renal-cell-carcinoma-1">renal cell carcinoma</a>, and is the enlargement the liver without hepatic metastases. It is a cause of cholestasis and cholestatic <a href="/articles/jaundice">jaundice</a>. </p><h4>History and etymology</h4><p>It is named after <strong>Maurice H. Stauffer</strong>, American gastroenterologist who first described it in 1961.</p>
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