Technetium-99m agents

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Technetium agents based on the technetium-99m(Tc-99m) radioisotope are frequently used agents in medical imaging. The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific radiopharmaceuticals and optimise the functional imaging of various structures:

Tctechnetium-99m ECD: CNS imaging
Tctechnetium-99m GHA : oncological imaging (e.g. low-grade glioma, lung)
Tctechnetium-99m sulfur colloid
- splenic and hepatic imaging
- taken up by the spleen, Kupffer cells in the liver and a small proportion by bone marrow
- bone marrow and soft tissue infection scintigraphy
- lymphatic scintigraphy, e.g. sentinel node lymphoscintigraphy
Tctechnetium-99m pertechnetate
- thyroid imaging
- Meckel scan
- testicular scintigraphy
- parathyroid subtraction study
- gastric emptying, intestinal and rectal functional studies
Tctechnetium-99m MDP: bone scintigraphy
Tctechnetium-99m MAA: lung perfusion imaging
Tctechnetium-99m teboroxime: cardiac imaging
Tctechnetium-99m metformin
Tctechnetium-99m MIBI
- cardiac imaging
- parathyroid imaging
Tc
technetium-99m HIDA : hepatobiliary scintigraphy
Tctechnetium-99m HMPAO: cerebral perfusion imaging
Tctechnetium-99m HMPAO labelled WBC: infection scintigraphy
Tctechnetium-99m-labeled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis
Tctechnetium-99m labelled RBC
- assessment of occult gastrointestinal haemorrhage
- assessment of vascular lesions, e.g. hepatic haemangioma
- assessment of cardiac function, first pass or equilibrium
Tctechnetium-99m labelled heat-denatured RBC: specific splenic assessment, gold-standard in splenosis
Tctechnetium-99m MAG3: renal imaging
Tctechnetium-99m DMSA: renal cortical imaging
technetium-99m DTPA: glomerular renal imaging, glomerular filtration ratio
Tctechnetium-99m DTPA (aerosol): lung ventilation imaging, bronchial clearance
Tctechnetium-99m sestamibi: parathyroid imaging

-Technetium agents based on the <a href="/articles/technetium-99m">technetium-99m</a> (Tc-99m) radioisotope are frequently used agents in medical imaging. The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific <a href="/articles/radiopharmaceuticals">radiopharmaceuticals</a> and optimise the functional imaging of various structures:<ul>
+Technetium agents based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific <a href="/articles/radiopharmaceuticals">radiopharmaceuticals</a> and optimise the functional imaging of various structures:<ul>
~~-<a href="/articles/tc-99m-ecd">Tc-99m ECD</a>: CNS imaging</li>~~
~~-<li>Tc-99m GHA : oncological imaging (e.g. low-grade glioma, lung)</li>~~
+<a href="/articles/tc-99m-ecd">technetium-99m ECD</a>: CNS imaging</li>
+<li>technetium-99m GHA : oncological imaging (e.g. low-grade glioma, lung)</li>
~~-<a href="/articles/tc-99m-sulfur-colloid-4">Tc-99m sulfur colloid</a><ul>~~
+<a href="/articles/tc-99m-sulfur-colloid-4">technetium-99m sulfur colloid</a><ul>
~~-<a href="/articles/tc-99m-pertechnetate">Tc-99m pertechnetate</a><ul>~~
+<a href="/articles/tc-99m-pertechnetate">technetium-99m pertechnetate</a><ul>
~~-<a href="/articles/technetium-99m-methyl-diphosphonate">Tc-99m MDP</a>: bone scintigraphy</li>~~
+<a href="/articles/technetium-99m-methyl-diphosphonate">technetium-99m MDP</a>: bone scintigraphy</li>
~~-<a href="/articles/tc-99m-maa">Tc-99m MAA</a>: lung perfusion imaging</li>~~
+<a href="/articles/tc-99m-maa">technetium-99m MAA</a>: lung perfusion imaging</li>
~~-<a href="/articles/tc-99m-teboroxime">Tc-99m teboroxime</a>: cardiac imaging</li>~~
~~-<li>Tc-99m metformin</li>~~
+<a href="/articles/tc-99m-teboroxime">technetium-99m teboroxime</a>: cardiac imaging</li>
+<li>technetium-99m metformin</li>
~~-<a href="/articles/tc-99m-mibi">Tc-99m MIBI</a><ul>~~
+<a href="/articles/tc-99m-mibi">technetium-99m MIBI</a><ul>
~~-</ul>Tc-99m HIDA : hepatobiliary scintigraphy</li>~~
+</ul>
+</li>
+<li>technetium-99m HIDA : hepatobiliary scintigraphy</li>
~~-<a href="/articles/tc-99m-hmpao">Tc-99m HMPAO</a>: cerebral perfusion imaging</li>~~
+<a href="/articles/tc-99m-hmpao">technetium-99m HMPAO</a>: cerebral perfusion imaging</li>
~~-<a href="/articles/tc-99m-hmpao-labelled-wbc">Tc-99m HMPAO labelled WBC</a>: infection scintigraphy</li>~~
~~-<li>Tc-99m-labeled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis</li>~~
+<a href="/articles/tc-99m-hmpao-labelled-wbc">technetium-99m HMPAO labelled WBC</a>: infection scintigraphy</li>
+<li>technetium-99m-labeled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis</li>
~~-<a href="/articles/tc-99m-labeled-rbc">Tc-99m labelled RBC</a><ul>~~
+<a href="/articles/tc-99m-labeled-rbc">technetium-99m labelled RBC</a><ul>
~~-<li>Tc-99m labelled heat-denatured RBC: specific splenic assessment, gold-standard in <a href="/articles/splenosis">splenosis</a>~~
+<li>technetium-99m labelled heat-denatured RBC: specific splenic assessment, gold-standard in <a href="/articles/splenosis">splenosis</a>
~~-<a href="/articles/tc-99m-mag3">Tc-99m MAG3</a>: renal imaging</li>~~
+<a href="/articles/tc-99m-mag3">technetium-99m MAG3</a>: renal imaging</li>
~~-<a href="/articles/tc-99m-dmsa">Tc-99m DMSA</a>: renal cortical imaging</li>~~
+<a href="/articles/tc-99m-dmsa">technetium-99m DMSA</a>: renal cortical imaging</li>
~~-<a href="/articles/tc-99m-dtpa">Tc-99m DTPA</a>: glomerular renal imaging, glomerular filtration ratio</li>~~
+<a title="Technetium-99m diethylene-triamine-pentaacetate" href="/articles/tc-99m-dtpa">technetium-99m DTPA</a>: glomerular renal imaging, glomerular filtration ratio</li>
~~-<a href="/articles/tc-99m-dtpa-aerosol">Tc-99m DTPA (aerosol)</a>: lung ventilation imaging, bronchial clearance</li>~~
+<a href="/articles/tc-99m-dtpa-aerosol">technetium-99m DTPA (aerosol)</a>: lung ventilation imaging, bronchial clearance</li>
~~-<a href="/articles/tc-99m-sestamibi">Tc-99m sestamibi</a>: parathyroid imaging</li>~~
+<a href="/articles/tc-99m-sestamibi">technetium-99m sestamibi</a>: parathyroid imaging</li>

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Technetium-99m agents

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