Testicular choriocarcinoma

Changed by Subhan Iqbal, 17 Sep 2022
Disclosures - updated 17 Sep 2022: Nothing to disclose

Updates to Article Attributes

Body was changed:

Testicular choriocarcinoma is a type of non-seminomatous germ cell tumour

Epidemiology

Incidence peaks at around 20-30 years of age.

Clinical presentation

Can be variable with some patients initially presenting with metastases.

Pathology

It is most commonly detected as a component of a mixed malignant germ cell tumour and observed in about 7-8% of testicular tumours. It is extremely rare in pure form, choriocarcinoma comprising only 0.2-0.6% of all testis tumours.

Markers

b-HCG levels tend to be elevated

Treatment and prognosis 

It is considered an aggressive malignancy. Choriocarcinoma can often spread haematogenously. Treatment options include orchidectomy +/- combination chemotherapy.

See also

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