Toxic leukoencephalopathy (mnemonic)

Last revised by Rohit Sharma on 21 Feb 2024

Citation, DOI, disclosures and article data

Citation:

Deng F, Sharma R, Yap J, et al. Toxic leukoencephalopathy (mnemonic). Reference article, Radiopaedia.org (Accessed on 27 Apr 2024) https://doi.org/10.53347/rID-74476

DOI:

https://doi.org/10.53347/rID-74476

Permalink:

https://radiopaedia.org/articles/74476

rID:

74476

Article created:

24 Feb 2020, Francis Deng ◉

Disclosures:

At the time the article was created Francis Deng had no recorded disclosures.

View Francis Deng's current disclosures

Last revised:

21 Feb 2024, Rohit Sharma ◉

Disclosures:

At the time the article was last revised Rohit Sharma had no financial relationships to ineligible companies to disclose.

View Rohit Sharma's current disclosures

Revisions:

4 times, by 4 contributors - see full revision history and disclosures

Systems:

Central Nervous System

Sections:

Mnemonics

A mnemonic to remember the more common causes of toxic leukoencephalopathy is:

CHOICES ¹

Mnemonic

C: chemotherapy (e.g. methotrexate)
H: heroin
O: other opioids
I: immunosuppressant drugs or imidazole
C: cocaine
E: ethanol or environmental (e.g. carbon monoxide)
S: splenial lesions (reversible secondary to: CLOCCs, antiseizure medications, chemotherapy, immunosuppressant drugs, etc.)