Vagal paraganglioma
Updates to Article Attributes
Glomus vagale tumours are paragangliomas that occur along the path of the vagus nerve (CN X). They are a subset of extra-adrenal neuroendocrine tumours that are derived from the nonchromaffin paraganglion cells.
Clinical presentation
Typically presents as a painless mass behind the carotid artery. Vocal cord paralysis is a relatively frequent finding (~47%) 3.
Pathology
For a general discussion on the pathology for these tumours, please refer to the parental article on paragangliomas.
Location
Although they could occur at a similar position to carotid body tumours they tend to be more rostral in location and do not widen the carotid bifurcation. They displace the internal and external carotid arteries anteriorly, and the internal jugular vein posteriorly 1.
Radiographic features
Ultrasound
Difficult to sonographically differentiate between other lesions that can potentially occur in this location. MayIt may be seen as a solid heterogeneously hypoechoic lesion comprising of small vascular structures 3.
MRI
- T1: usually low signal
- T2: high signal with multiple flow voids, which may give a salt and pepper appearance
- T1C+: intense enhancement
Differential diagnoses
The differential for lesions in this location include 2,4:
- vagal schwannoma/neurofibroma
- carotid space meningioma (extends from jugular foramen)
-<p><strong>Glomus vagale tumours</strong> are <a href="/articles/paraganglioma-1">paragangliomas</a> that occur along the path of the <a href="/articles/vagus-nerve-cn-x">vagus nerve (CN X)</a>. They are a subset of extra-adrenal neuroendocrine tumours that are derived from the <a href="/articles/nonchromaffin-paraganglion-cells">nonchromaffin paraganglion cells</a>. </p><h4>Clinical presentation</h4><p>Typically presents as a painless mass behind the carotid artery. Vocal cord paralysis is a relatively frequent finding (~47%) <sup>3</sup>.</p><h4>Pathology</h4><p>For a general discussion on the pathology for these tumours, please refer to the parental article on <a href="/articles/paraganglioma-1">paragangliomas</a>. </p><h5>Location</h5><p>Although they could occur at a similar position to <a href="/articles/carotid-body-tumour">carotid body tumours</a> they tend to be more rostral in location and do not widen the <a href="/articles/carotid-bifurcation">carotid bifurcation</a>. They displace the <a href="/articles/internal-carotid-artery-1">internal</a> and <a href="/articles/external-carotid-artery-1">external carotid arteries</a> anteriorly, and the <a href="/articles/internal-jugular-vein">internal jugular vein</a> posteriorly <sup>1</sup>.</p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Difficult to sonographically differentiate between other lesions that can potentially occur in this location. May be seen as a solid heterogeneously hypoechoic lesion comprising of small vascular structures <sup>3</sup>.</p><h5>MRI</h5><ul>- +<p><strong>Glomus vagale tumours</strong> are <a href="/articles/paraganglioma-1">paragangliomas</a> that occur along the path of the <a href="/articles/vagus-nerve-cn-x">vagus nerve (CN X)</a>. They are a subset of extra-adrenal neuroendocrine tumours that are derived from the <a href="/articles/nonchromaffin-paraganglion-cells">nonchromaffin paraganglion cells</a>. </p><h4>Clinical presentation</h4><p>Typically presents as a painless mass behind the carotid artery. Vocal cord paralysis is a relatively frequent finding (~47%) <sup>3</sup>.</p><h4>Pathology</h4><p>For a general discussion on the pathology for these tumours, please refer to the parental article on <a href="/articles/paraganglioma-1">paragangliomas</a>. </p><h5>Location</h5><p>Although they could occur at a similar position to <a href="/articles/carotid-body-tumour">carotid body tumours</a> they tend to be more rostral in location and do not widen the <a href="/articles/carotid-bifurcation">carotid bifurcation</a>. They displace the <a href="/articles/internal-carotid-artery-1">internal</a> and <a href="/articles/external-carotid-artery-1">external carotid arteries</a> anteriorly, and the <a href="/articles/internal-jugular-vein">internal jugular vein</a> posteriorly <sup>1</sup>.</p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Difficult to sonographically differentiate between other lesions that can potentially occur in this location. It may be seen as a solid heterogeneously hypoechoic lesion comprising small vascular structures <sup>3</sup>.</p><h5>MRI</h5><ul>
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