Vitamin B1

Changed by Daniel J Bell, 10 Jan 2019

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Vitamin B₁ (thiamine) is a water-soluble vitamin that is an important coenzyme for two reactions in the citric acid cycle (Kreb cycle). It therefore is vital for cellular ATP production, particularly in the central nervous system.

Terminology

Thiamine is the preferred official spelling, however thiamin is still seen, especially in the older literature, and more contemporaneously is often used in non-scientific writings. Thiamine is felt to more closely follow accepted chemical nomenclature as it is chemically an amine ². An obsolete term for thiamine is aneurin.

Related pathology

Pathological manifestations only occur with thiamine deficiency.

-Vitamin B1 (thiamine) is a water-soluble <a href="/articles/vitamins">vitamin</a> that is an important coenzyme for two reactions in the citric acid cycle (Kreb cycle). It therefore is vital for cellular ATP production, particularly in the central nervous system.<h4>
+Vitamin B1 (thiamine) is a water-soluble <a href="/articles/vitamins">vitamin</a> that is an important coenzyme for two reactions in the citric acid cycle (Kreb cycle). It therefore is vital for cellular ATP production, particularly in the central nervous system.<h4>Terminology</h4>Thiamine is the preferred official spelling, however thiamin is still seen, especially in the older literature, and more contemporaneously is often used in non-scientific writings. Thiamine is felt to more closely follow accepted chemical nomenclature as it is chemically an amine 2. An obsolete term for thiamine is aneurin. <h4>

References changed:

2. Williams RR. Thiamin or Thiamine?. (1949) Science (New York, N.Y.). 109 (2838): 525. <a href="https://doi.org/10.1126/science.109.2838.525">doi:10.1126/science.109.2838.525</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/17830012">Pubmed</a>