WHO classification of odontogenic and maxillofacial bone tumors

Changed by Joachim Feger, 2 Aug 2021

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The WHO classification of odontogenic and maxillofacial bone tumours, last published in 2017, is a subset of the WHO classification of head and neck tumors (4^th edition), that lays out a histological classification system for neoplasms and other tumours related to the odontogenic apparatus.

Classification

Malignant odontogenic tumours

odontogenic carcinomas
- ameloblastic carcinoma
- primary intraosseous carcinoma, not otherwise specified
- sclerosing odontogenic carcinoma
- clear cell odontogenic carcinoma
- ghost cell odontogenic carcinoma
odontogenic carcinosarcoma
odontogenic sarcomas

Benign odontogenic tumours

benign epithelial odontogenic tumours
- ameloblastoma
  - ameloblastoma, unicystic type
  - ameloblastoma, extraosseous/peripheral type
  - metastasising ameloblastoma
- squamous odontogenic tumour
- calcifying epithelial odontogenic tumour
- adenomatoid odontogenic tumour
benign mixed epithelial and mesenchymal odontogenic tumours
- ameloblastic fibroma
- primordial odontogenic tumour
- odontoma
- dentinogenic ghost cell tumour
benign mesenchymal odontogenic tumours
- odontogenic fibroma
- odontogenic myxoma/myxofibroma
- cementoblastoma
- cemento -ossifying fibroma

Odontogenic cyst

odontogenic cysts of inflammatory origin
- radicular cyst
- inflammatory collateral cysts
odontogenic and non-odontogenic developmental cysts
- dentigerous cyst
- odontogenic keratocyst
- lateral periodontal cyst and botryoid odontogenic cyst
- gingival cysts
- glandular odontogenic cyst
- calcifying odontogenic cyst
- orthokeratinized odontogenic cyst
- nasopalatine duct cyst

Malignant maxillofacial bone and cartilage tumors

Benign maxillofacial bone and cartilage tumors

Fibro-osseous and osteochondromatous lesions

Giant cell lesions and simple bone cyst

Hematolymphoid tumors

solitary plasmacytoma of bone

-<p>The <strong>WHO classification of odontogenic and maxillofacial bone tumours</strong>, last published in 2017, is a subset of the <a title="WHO classification of head and neck tumors" href="/articles/who-classification-of-head-and-neck-tumors">WHO classification of head and neck tumors</a> (4<sup>th</sup> edition), that lays out a histological classification system for neoplasms and other tumours related to the odontogenic apparatus.</p><h4>Classification</h4><h5>Malignant odontogenic tumours</h5><ul>
+<p>The <strong>WHO classification of odontogenic and maxillofacial bone tumours</strong>, last published in 2017, is a subset of the <a href="/articles/who-classification-of-head-and-neck-tumors">WHO classification of head and neck tumors</a> (4<sup>th</sup> edition), that lays out a histological classification system for neoplasms and other tumours related to the odontogenic apparatus.</p><h4>Classification</h4><h5>Malignant odontogenic tumours</h5><ul>
~~-<li>ameloblastic carcinoma</li>~~
+<li><a href="/articles/ameloblastic-carcinoma">ameloblastic carcinoma</a></li>
~~-<li>dentinogenic ghost cell tumour</li>~~
+<li><a title="Dentinogenic ghost cell tumour" href="/articles/dentinogenic-ghost-cell-tumour">dentinogenic ghost cell tumour</a></li>
~~-<li>odontogenic fibroma</li>~~
+<li><a title="Odontogenic fibroma" href="/articles/odontogenic-fibroma">odontogenic fibroma</a></li>

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