Young syndrome
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Young syndrome shares similar clinical and radiological findings to primary ciliary dyskinesia and cystic fibrosis, however, the underlying pathogenesis is yet to be fully elucidated. Obstructive azoospermia at the level of the epididymis is thought to be the cause of infertility. The commonly referenced clinical triad is 1:
- obstructive azoospermia
- bronchiectasis (predominantly lower lobe)
-
sinusitis (although well known as part of the triad, sinusitis in Young
'ssyndrome is based on case reports/ case series/series and has not been well documented in research) 2
EtymologyHistory and etymology
It is named after Donald Young, a urologist who first reported a series of patients with obstructive azoospermia in association with respiratory pathology in 1970 4.
See also
-<p><strong>Young syndrome</strong> shares similar clinical and radiological findings to <a href="/articles/primary-ciliary-dyskinesia">primary ciliary dyskinesia</a> and cystic fibrosis, however, the underlying pathogenesis is yet to be fully elucidated. Obstructive azoospermia at the level of the epididymis is thought to be the cause of infertility. The commonly referenced clinical triad is <sup>1</sup>:</p><ul>- +<p><strong>Young syndrome</strong> shares similar clinical and radiological findings to <a href="/articles/primary-ciliary-dyskinesia">primary ciliary dyskinesia</a> and <a title="Cystic fibrosis" href="/articles/cystic-fibrosis">cystic fibrosis</a>, however, the underlying pathogenesis is yet to be fully elucidated. Obstructive azoospermia at the level of the epididymis is thought to be the cause of infertility. The commonly referenced clinical triad is <sup>1</sup>:</p><ul>
-<a href="/articles/chronic-sinusitis">sinusitis</a> (although well known as part of the triad, sinusitis in Young's syndrome is based on case reports/ case series and has not been well documented in research) <sup>2</sup>- +<a href="/articles/chronic-sinusitis">sinusitis</a> (although well known as part of the triad, sinusitis in Young syndrome is based on case reports/series and has not been well documented in research) <sup>2</sup>
-</ul><h4>Etymology</h4><p>It is named after <strong>Donald Young</strong>, a urologist who first reported a series of patients with <a href="/articles/obstructive-azoospermia">obstructive azoospermia</a> in association with respiratory pathology. </p><h4>See also</h4><ul><li><a href="/articles/kartagener-syndrome-1">Kartagener syndrome</a></li></ul>- +</ul><h4>History and etymology</h4><p>It is named after <strong>Donald Young</strong>, a urologist who first reported a series of patients with <a href="/articles/obstructive-azoospermia">obstructive azoospermia</a> in association with respiratory pathology in 1970 <sup>4</sup>. </p><h4>See also</h4><ul><li><a href="/articles/kartagener-syndrome-1">Kartagener syndrome</a></li></ul>
References changed:
- 4. Young D. Surgical treatment of male infertility. J Reprod Fertil 1970;23:541-2
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