Presentation
Palpable mass in the left breast.
Patient Data
A. Mediolateral oblique mammogram of the left breast shows an extremely dense, type D (ACR), and a high-density mass with obscured and indistinct margins, located in the upper internal quadrant, posterior third.
B. Craniocaudal mammogram of the left breast shows a high-density mass with obscured margins.
Hypoechoic heterogeneous irregular mass with indistinct margins, anechoic areas, posterior shadow, and internal vascularity.
Core biopsy of the solid irregular heterogeneous mass.
FDG PET-CT of the left breast located in the upper internal quadrant shows focal hypermetabolism.
Compare with the CT simple, shows a homogenous mass.
Case Discussion
Diagnosis:
LARGE CELL DIFFUSE NON-HODGKIN LYMPHOMA.
Immunohistochemistry:
CD 20 Positive
CD 3 Positive
CKAE/AE3 Negative
CKAE/AE3 Negative
CD3 POSITIVE IN REACTIVE LYMPHOCYTES
Breast lymphoma is hematologic cancer and a rare tumor and represents 0.04- 0.7% of all breast. Represents 0.38-0.7% of all non-Hodgkin lymphomas.
This cancer is very aggressive and affects old women 60-85 years.
Are divided into primary and secondary. The first has many subtypes and the most common is a diffuse large B cell lymphoma approximately 45-79% and Burkitt lymphoma is associated with people VIH +, pregnancies, and women in lactation, and represents only 10%.