L-asparaginase induced pancreatitis in childhood acute lymphoblastic leukemia
Diagnosis almost certain
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L-asparaginase has been part of the treatment of childhood onset ALL for many decades now. L-asparaginase induced pancreatitis is known to be a major complication of this treatment, but the pathophysiology behind this is still to be found.
Further reading HERE.
-<p>L-asparaginase has been part of the treatment of childhood onset <a href="/articles/acute-lymphoblastic-leukemia" title="acute lymphoblastic leukemia">ALL</a> for many decades now. L-asparaginase induced <a href="/articles/acute-pancreatitis" title="Acute pancreatitis">pancreatitis </a>is known to be a major complication of this treatment, but the pathophysiology behind this is still to be found. </p><p>Further reading <a href="Raja%20RA,%20Schmiegelow%20K,%20Frandsen%20TL.%20Asparaginase-associated%20pancreatitis%20in%20children.%20Br.%20J.%20Haematol.%202012;159%20(1):%2018-27.%20<a%20href=%22http://dx.doi.org/10.1111/bjh.12016%22>doi:10.1111/bjh.12016</a>%20-%20<a%20href=%22http://www.ncbi.nlm.nih.gov/pubmed/22909259%22>Pubmed%20citation</a><div%20class=%22ref_v2%22></div>" title="HERE">HERE</a>.</p>- +<p>L-asparaginase has been part of the treatment of childhood onset <a href="/articles/acute-lymphoblastic-leukemia">ALL</a> for many decades now. L-asparaginase induced <a href="/articles/acute-pancreatitis">pancreatitis </a>is known to be a major complication of this treatment, but the pathophysiology behind this is still to be found. </p>
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