Lymphoplasmacyte-rich meningioma

Case contributed by Dalia Ibrahim , 15 Aug 2019
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Lymphoplasmacyte-rich meningiomas are rare histological variants of benign (WHO grade I) meningiomas, characterised by prominent lymphoplasmacytic infiltrates into the tumour, sometimes rendering the underlying meningothelial component inconspicuous.

Clinical features include a predilection for relatively young patients, often with secondary hypergammaglobulinemia and anemia.

Typically, the tumor is hyperdense on non-contrast CT and iso- to hypointense on T1-weighted images. T2-weighted images show mixed hyper- to iso-intensity more often than iso- to hypointensity. Diffusion restriction can be seen.Post-contrast MR images show strong and homogeneous enhancement.Cyst formation can be detected in 30 % and peritumoral brain edema in nearly 100 % of the cases.

Case courtesy f Dr. Amr Abdel Fatah, Lecturer of Radiodiagnosis, Kasr Al Ainy Hospital.

  • -<p><a title="Lymphoplasmacyte-rich meningiomas" href="/articles/lymphoplasmacyte-rich-meningiomas"><strong>Lymphoplasmacyte-rich meningiomas</strong></a> are rare histological variants of benign (WHO grade I) <a href="/articles/meningioma">meningiomas</a>, characterised by prominent lymphoplasmacytic infiltrates into the tumour, sometimes rendering the underlying meningothelial component inconspicuous.</p><p>Clinical features include a predilection for relatively young patients, often with secondary hypergammaglobulinemia and anemia.</p><p>Typically, the tumor is hyperdense on non-contrast CT and iso- to hypointense on T1-weighted images. T2-weighted images show mixed hyper- to iso-intensity more often than iso- to hypointensity. Diffusion restriction can be seen.Post-contrast MR images show strong and homogeneous enhancement.Cyst formation can be detected in 30 % and peritumoral brain edema in nearly 100 % of the cases.</p><p> </p><p> </p>
  • +<p><a href="/articles/lymphoplasmacyte-rich-meningiomas"><strong>Lymphoplasmacyte-rich meningiomas</strong></a> are rare histological variants of benign (WHO grade I) <a href="/articles/meningioma">meningiomas</a>, characterised by prominent lymphoplasmacytic infiltrates into the tumour, sometimes rendering the underlying meningothelial component inconspicuous.</p><p>Clinical features include a predilection for relatively young patients, often with secondary hypergammaglobulinemia and anemia.</p><p>Typically, the tumor is hyperdense on non-contrast CT and iso- to hypointense on T1-weighted images. T2-weighted images show mixed hyper- to iso-intensity more often than iso- to hypointensity. Diffusion restriction can be seen.Post-contrast MR images show strong and homogeneous enhancement.Cyst formation can be detected in 30 % and peritumoral brain edema in nearly 100 % of the cases.</p><p><em>Case courtesy f Dr. Amr Abdel Fatah, Lecturer of Radiodiagnosis, Kasr Al Ainy Hospital.</em></p>

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Lymphoplasmacyte-rich meningioma

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