Meningothelial hyperplasia and superficial cortical vein attenuation

Case contributed by Angel Donato , 2 Feb 2017
Diagnosis certain
Changed by Sachi Hapugoda, 3 Jun 2017

Updates to Case Attributes

Age changed from 42 to 40.
Presentation was changed:
A 42 year old male veteran presentedPresented to ER who developedwith hallucinations and delirium. He had had 3 LPs w/normal cell count, elevated protein. He had had a 24 EEG on and off Depakote which did not show seizures. Physical Physical exam showed decreaserevealed decreased sensation onto the left face and palm of landthe hand Neurosurgery service doing a stereotactic biopsy because. Three lumbar punctures were completed with normal cell counts and elevated protein levels. A twenty-four hour EEG (on and off valproate) found no evidence of the MRI findings.seizure activity.
Body was changed:

Meningothelial Hyperplasia (MH) is a poorly characterized entity and occasionally causes diagnostic difficulties due to its overlapping histologic features with meningioma.

MH is a reactive process characterized by a proliferation of meningothelial cells that reaches a thickness of 10ten or more cell layers with PR positivity, which is not seen in normal cells.

Brain MRI shows an remarkable accentuation of the parenchymal vessels throughout the full-thickness thickness of the cortex and whittewhite matter. 

This case was presented in Eurorad,  but.

Due to the authors want to share with radiopaediaMRI findings, a stereotactic biopsy was performed by the treating neurosurgical team.

  • -<p>Meningothelial Hyperplasia (MH) is a poorly characterized entity and occasionally causes diagnostic difficulties due to its overlapping histologic features with meningioma.</p><p>MH is a reactive process characterized by a proliferation of meningothelial cells that reaches a thickness of 10 or more cell layers with PR positivity, which is not seen in normal cells.</p><p>Brain MRI shows an remarkable accentuation of parenchymal vessels throughout the full-thickness of the cortex and whitte matter. </p><p>This case was presented in Eurorad,  but the authors want to share with radiopaedia. </p>
  • +<p>Meningothelial Hyperplasia (MH) is a poorly characterized entity and occasionally causes diagnostic difficulties due to its overlapping histologic features with meningioma.</p><p>MH is a reactive process characterized by a proliferation of meningothelial cells that reaches a thickness of ten or more cell layers with PR positivity, which is not seen in normal cells.</p><p>Brain MRI shows remarkable accentuation of the parenchymal vessels throughout the full thickness of the cortex and white matter. </p><p>This case was presented in <em>Eurorad</em>.</p><p>Due to the MRI findings, a stereotactic biopsy was performed by the treating neurosurgical team.</p>

References changed:

  • 1. Donato A, Figueroa R. Meningothelial Hyperplasia. EuroRad <a href="https://doi.org/10.1594/EURORAD/CASE.14675">doi:10.1594/EURORAD/CASE.14675</a> <span class="ref_v4"></span>
  • http://www.eurorad.org/eurorad/case.php?id=14675
  • Donato A, Figueroa R. Meningothelial Hyperplasia. EuroRad. Case 14675 6. href="https://http://www.eurorad.org/eurorad/case.php?id=14675">doi:10.1594/EURORAD/CASE.14675</a>

Updates to Study Attributes

Findings was changed:

MR Brain MRI demonstratedemonstrates diffuse engorgement and accentuation of parenchymlthe parenchymal vessels.

Images Changes:

Image MRI (T1 C+) ( update )

Description was changed:
Gadolinium-enhanced imagesdemonstrate diffuse engorgement of multiple vascular structures extending from hemispheric cortex through subcortical white matter, deep white matter and subependymal margins on both cerebral hemispheres as well as throughout cerebellum and brainstem.

Image MRI (SWI) ( update )

Description was changed:
Susceptibility weighted images demonstrates a demonstrate remarkable accentuation of the parenchymal vessels.

Image MRI (MRA) ( update )

Description was changed:
There is no recognizable venous obstruction to account for vascular engorgement. There is not a dural fistula.

Image MRI (T1 C+) ( update )

Description was changed:
Gadolinium-enhanced imagesdemonstrate diffuse engorgement of multiple vascular structures extending from hemispheric cortex through subcortical white matter, deep white matter and subependymal margins on both cerebral hemispheres as well as throughout cerebellum and brainstem.

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