Meningothelial hyperplasia and superficial cortical vein attenuation

Case contributed by Angel Donato , 2 Feb 2017
Diagnosis certain
Changed by Henry Knipe, 7 Dec 2018

Updates to Study Attributes

Findings was changed:

MR Brain demonstratesGadolinium-enhanced images demonstrate diffuse engorgement of multiple vascular structures extending from hemispheric cortex through subcortical white matter, deep white matter and subependymal margins on both cerebral hemispheres as well as throughout cerebellum and brainstem.

Susceptibility weighted images demonstrate remarkable accentuation of the parenchymal vessels.

There is no recognizable venous obstruction to account for vascular engorgement. There is not a dural fistula.

Images Changes:

Image MRI (T1 C+) ( update )

Description was removed:
Gadolinium-enhanced images demonstrate diffuse engorgement of multiple vascular structures extending from hemispheric cortex through subcortical white matter, deep white matter and subependymal margins on both cerebral hemispheres as well as throughout cerebellum and brainstem.

Image MRI (T1 C+) ( update )

Description was removed:
Gadolinium-enhanced images demonstrate diffuse engorgement of multiple vascular structures extending from hemispheric cortex through subcortical white matter, deep white matter and subependymal margins on both cerebral hemispheres as well as throughout cerebellum and brainstem.

Image MRI (SWI) ( update )

Description was removed:
Susceptibility weighted images demonstrate remarkable accentuation of the parenchymal vessels.

Image MRI (MRA) ( update )

Description was removed:
There is no recognizable venous obstruction to account for vascular engorgement. There is not a dural fistula.

Updates to Study Attributes

Findings was changed:

Cortical biopsy reports Meningothelialmeningothelial hyperplasia.

Updates to Quizquestion Attributes

Question was changed:
TheWhat is the feature that histologically helps distinguish meningothelial hyperplasia from normal arachnoidal cells is?

Updates to Quizquestion Attributes

Question was changed:
Meningothelial Hyperplasiahyperplasia is a reactive process characterized by a proliferation of what kind of cells?
Answer was changed:
Meningothelial Hyperplasiahyperplasia is a reactive process characterized by a proliferation of meningothelial cells that is often non-invasive, multicentric that reaches a thickness of 10 or more cell layers.

Updates to Case Attributes

Body was changed:

Due to the MRI findings, a stereotactic biopsy was performed by the treating neurosurgical team.

Meningothelial hyperplasia is a poorly characterized entity and occasionally causes diagnostic difficulties due to its overlapping histologic features with meningioma. It is a reactive process characterized by a proliferation of meningothelial cells that reaches a thickness of ten or more cell layers with PR positivity, which is not seen in normal cells.

In this case, the brain MRI shows remarkable accentuation of the parenchymal vessels throughout the full thickness of the cortex and white matter. 

The relationship between the vascular attenuation and the histological finding of meningothelial hyperplasia is unclear and a causal relationship has not been firmly established. 

This case was presented in Eurorad.

  • -<p>Due to the MRI findings, a stereotactic biopsy was performed by the treating neurosurgical team.</p><p><a title="Meningothelial hyperplasia" href="/articles/meningothelial-hyperplasia">Meningothelial hyperplasia</a> is a poorly characterized entity and occasionally causes diagnostic difficulties due to its overlapping histologic features with meningioma. It is a reactive process characterized by a proliferation of meningothelial cells that reaches a thickness of ten or more cell layers with PR positivity, which is not seen in normal cells.</p><p>In this case, the brain MRI shows remarkable accentuation of the parenchymal vessels throughout the full thickness of the cortex and white matter. </p><p>The relationship between the vascular attenuation and the histological finding of meningothelial hyperplasia is unclear and a causal relationship has not been firmly established. </p><p>This case was presented in <em>Eurorad</em>.</p>
  • +<p>Due to the MRI findings, a stereotactic biopsy was performed by the treating neurosurgical team.</p><p><a href="/articles/meningothelial-hyperplasia">Meningothelial hyperplasia</a> is a poorly characterized entity and occasionally causes diagnostic difficulties due to its overlapping histologic features with meningioma. It is a reactive process characterized by a proliferation of meningothelial cells that reaches a thickness of ten or more cell layers with PR positivity, which is not seen in normal cells.</p><p>In this case, the brain MRI shows remarkable accentuation of the parenchymal vessels throughout the full thickness of the cortex and white matter. </p><p>The relationship between the vascular attenuation and the histological finding of meningothelial hyperplasia is unclear and a causal relationship has not been firmly established. </p><p>This case was presented in <em>Eurorad</em>.</p>

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