Pyogenic liver abscess - cluster sign

Case contributed by Bijaya Shrestha , 10 Sep 2021
Diagnosis almost certain
Changed by Mostafa Elfeky, 20 Sep 2021

Updates to Case Attributes

Title was changed:
ClusterPyogenic liver abscess - cluster sign
Body was changed:

The cluster sign is a finding associated with pyogenic liver abscesses. It is better appreciated on  contrastcontrast-enhanced CT and MRI images. The sign describes the coalescence of multiple tiny abscesses into a single larger abscess cavity with peripheral rim enhancement on post-contrast studies, giving a clustered appearance. 

  • -<p>The <a title="Cluster sign" href="/articles/cluster-sign">cluster sign</a> is a finding associated with <a title="Pyogenic liver abscess" href="/articles/hepatic-abscess-1">pyogenic liver abscesses</a>. It is better appreciated on  contrast-enhanced CT and MRI images. The sign describes the coalescence of multiple tiny abscesses into a single larger abscess cavity with peripheral rim enhancement on post-contrast studies, giving a clustered appearance. </p>
  • +<p>The <a href="/articles/cluster-sign">cluster sign</a> is a finding associated with <a href="/articles/hepatic-abscess-1">pyogenic liver abscesses</a>. It is better appreciated on contrast-enhanced CT and MRI images. The sign describes the coalescence of multiple tiny abscesses into a single larger abscess cavity with peripheral rim enhancement on post-contrast studies, giving a clustered appearance. </p>

References changed:

  • 1. Jeffrey R, Tolentino C, Chang F, Federle M. CT of Small Pyogenic Hepatic Abscesses: The Cluster Sign. AJR Am J Roentgenol. 1988;151(3):487-489. <a href="https://doi.org/10.2214/ajr.151.3.487">doi:10.2214/ajr.151.3.487</a>
  • Jeffrey R, Tolentino C, Chang F, Federle M. CT of Small Pyogenic Hepatic Abscesses: The Cluster Sign. AJR Am J Roentgenol. 1988;151(3):487-489. <a href="https://doi.org/10.2214/ajr.151.3.487">doi:10.2214/ajr.151.3.487</a>

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Title was removed:
Cluster sign
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Findings was changed:

There is a large, well-defined hypodense lesion with septations and cluster sign involving the segments VI and VII in the right lobe of the liver. It measures approximately 9.6 cm x 10 cm x 11 cm. These lesions show peripheral enhancement on the arterial phase that persistpersists in the portal and delayed phase with non-enhancing central areas of diminished attenuation on post-contrast studies. A few enhancing septa are also present in the lesion.

Mild right reactionary pleural effusion.

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