Articles

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2,954 results found
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Parasellar dark T2 signal sign

The parasellar dark T2 signal sign is a MRI feature where there is parasellar low T2 signal. Some authors describe it as a specific finding in differentiating lymphocytic hypophysitis from a pituitary adenoma.
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Dragonfly sign

Dragonfly sign describes the appearance of the cerebellum on coronal images, which is seen secondary to cerebellar atrophy in pontocerebellar hypoplasia 1. The sign is so called as the whole cerebellum resembles the shape of a dragonfly if one imagines the vermis is the body of the insect and t...
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Double panda sign

The double panda sign refers to the combination of the face of the giant panda and face of the miniature panda (cub of the giant panda) seen on T2 weighted images of midbrain and pons respectively, most commonly seen in Wilson disease. The midbrain face of the giant panda sign consists of norma...
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Bardet-Biedl syndrome

Bardet-Biedl syndrome (BBS), previously known as the Laurence-Moon-Bardet-Biedl syndrome (LMBBS), is a rare autosomal recessive hereditary condition. Clinical presentation The clinical spectrum includes: retinal anomalies: similar to that of retinitis pigmentosa intellectual disability rena...
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AIDS-related diffuse large B-cell lymphoma

AIDS-related diffuse large B-cell lymphomas are one of the immunodeficiency-associated CNS lymphomas, and in Western countries represented a dramatic increase in primary CNS lymphoma during the HIV/AIDS epidemic of the 1980s, although the incidence is likely lower in patients treated with antire...
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Osmotic demyelination syndrome

Osmotic demyelination syndrome refers to acute demyelination seen in the setting of osmotic changes, typically with the rapid correction of hyponatremia. It is the preferred term replacing central pontine myelinolysis, recognizing that extrapontine structures can also be affected, previously kno...
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Bilateral thalamic glioma

Bilateral thalamic gliomas are rare but characteristic low-grade astrocytomas that occur in both children and young adults. Clinical presentation Presentation may vary with age. Young children with bilateral thalamic glioma often have signs of increased intracranial pressure and movement disor...
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Cacosmia

Cacosmia refers to a form of olfactory dysfunction where the patient has an inability to "recognize" smells. It can arise from a number of pathologies and can include peripheral sinonasal and central sensorineural components. In this situation, the patient knows there is a smell but cannot disti...
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Thumb sign (chordoma)

The thumb sign or thumbing of the pons is described in chordomas as is meant to be relatively specific. It is seen in midline sagittal projection as a projection of the tumor indenting the pons 1,2. See also thumb sign (disambiguation)
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Ageusia

Ageusia refers to a complete loss of taste. In instances where it is partial it is then falls under the spectrum of the conditions such as hypogeusia (decreased sensitivity to all tastants) hyperguesia (enhanced gustatory sensitivity) dysgeusia (unpleasant perception of a tastant) and phanto...
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Cryptococcoma

Cryptococcomas are a rare complication of infection by the Cryptococcus genus of invasive fungi, where a discrete, encapsulated lesion of immune infiltrates and pathogen forms. Cryptococcus gattii is most often isolated but Cryptococcus neoformans may also form cryptococcomas. Epidemiology In ...
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PHASES risk prediction score

The PHASES risk prediction score is a method of calculating the absolute 5-year risk of intracranial aneurysm rupture based on the data pooled from prospective cohort studies in the USA, Canada, Netherlands, Finland and Japan1. PHASES stands for: Population, Hypertension, Age, Size, Earlier suba...
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Chondrosarcoma

Chondrosarcomas are a heterogeneous group of malignant cartilaginous tumors most commonly found in older patients. They can arise de novo or secondary from an existing benign cartilaginous neoplasm. On imaging, these tumors have ring-and-arc chondroid matrix mineralization with aggressive featur...
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Posterior choroidal artery stroke

Posterior choroidal artery occlusion uncommonly presents as an isolated stroke syndrome.  It usually coexists with posterior cerebral artery and often superior cerebellar artery involvement.  When seen in isolation damage is characteristically limited to the: lateral geniculate body pulvinar ...
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Ganglion

A ganglion (plural: ganglia) is a group of neuronal cell bodies and processes located in the peripheral nervous system 1. Ganglia can be categorized into two groups - sensory ganglia and autonomic ganglia. Sensory ganglia primarily contain the cell bodies of neurons as well as their central an...
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CNS neuroblastoma, FOXR2-activated

Central nervous system neuroblastoma, FOXR2-activated is a novel brain tumor entity included in the WHO brain tumor classification 1. Terminology Central nervous system neuroblastoma with FOXR2 activation was identified in 2016 as a molecular entity, distinguished from primitive neuroectoderma...
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Medulloepithelioma of the optic disc and optic nerve

Medulloepitheliomas of the optic disc and optic nerve are extremely rare primary intraocular embryonal tumors arising from the optic disc and optic nerve. Terminology A medulloepithelioma of the optic disc and optic nerve may also be referred to as a diktyoma or teratoneuroma, although the use...
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Melioidosis

Melioidosis is an infectious disease caused by the bacterium Burkholderia pseudomallei (previously known as Pseudomonas pseudomallei) and is a multisystem disorder which may affect the lungs, brain, visceral organs, or musculoskeletal system. Epidemiology Melioidosis is a disease of the monsoo...
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Clival fracture

Clival fractures are uncommon skull base fractures resulting from high-energy cranial trauma and are usually associated with other skull vault fractures and brain injuries. For a general discussion, please refer to the article on basilar fractures of the skull. Epidemiology Most fractures of ...
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Multiple sclerosis

Multiple sclerosis (MS) is a relatively common acquired chronic demyelinating disease involving the central nervous system, and is the second most common cause of neurological impairment in young adults, after trauma 19. Characteristically, and by definition, multiple sclerosis is disseminated i...

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