Serous carcinoma of the endometrium
Updates to Article Attributes
Papillary serousSerous carcinoma of the endometrium is an uncommon histological subtype of endometrial carcinoma accounting for only 5-10% of all such tumours 2. It is considered type II endometrial adenocarcinoma and has a clinically aggressive form with an early extension of the tumour via Fallopianfallopian tubes into the peritoneum and peritoneal seeding which. This accounts for its poorer prognosis compared to the other adenocarcinomas of the uterus. This is thought to closely resemble ovarian papillary serous carcinoma 1.
Pathology
Like is ovarian counterpart, it is characterised by glandular growth patterns and/or papillary projections characterise it, and frequently contains psammoma bodies (may be found in ~1/3a third of cases) that may calcify 2.
Markers
This subtype may increase serum CA-125 levels 2.
-<p><strong>Papillary serous carcinoma of the endometrium</strong> is an uncommon histological subtype of <a href="/articles/endometrial-carcinoma">endometrial carcinoma</a> accounting for only 5-10% of all such tumours <sup>2</sup>. It is considered type II endometrial adenocarcinoma and has a clinically aggressive form with an early extension of the tumour via Fallopian tubes into the peritoneum and peritoneal seeding which accounts for its poorer prognosis compared to the other adenocarcinomas of the uterus. This is thought to closely resemble <a href="/articles/ovarian-serous-cystadenocarcinoma">ovarian papillary serous carcinoma</a> <sup>1</sup>.</p><h4>Pathology</h4><p>Like is ovarian counterpart papillary projections characterise it and frequently contains <a href="/articles/psammoma-bodies">psammoma bodies</a> (may be found in ~1/3 of cases) that may calcify <sup>2</sup>. </p><h5>Markers</h5><p>This subtype may increase serum <a href="/articles/ca-125">CA-125</a> levels <sup>2</sup>.</p>- +<p><strong>Serous carcinoma of the endometrium</strong> is an uncommon histological subtype of <a href="/articles/endometrial-carcinoma">endometrial carcinoma</a> accounting for only 5-10% of all such tumours <sup>2</sup>. It is has a clinically aggressive form with early extension of the tumour via fallopian tubes into the peritoneum and peritoneal seeding. This accounts for its poorer prognosis compared to the other adenocarcinomas of the uterus. This is thought to closely resemble <a href="/articles/ovarian-serous-cystadenocarcinoma">ovarian serous carcinoma</a> <sup>1</sup>.</p><h4>Pathology</h4><p>Like is ovarian counterpart, it is characterised by glandular growth patterns and/or papillary projections, and frequently contains <a href="/articles/psammoma-bodies">psammoma bodies</a> (may be found in a third of cases) that may calcify <sup>2</sup>. </p><h5>Markers</h5><p>This subtype may increase serum <a href="/articles/ca-125">CA-125</a> levels <sup>2</sup>.</p>
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