Psammoma bodies
Last revised by Joshua Yap on 6 May 2024
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Yap J, Yu Y, et al. Psammoma bodies. Reference article, Radiopaedia.org (Accessed on 16 May 2024) https://doi.org/10.53347/rID-1928
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1928
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Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Joshua Yap had no financial relationships to ineligible companies to disclose.
View Joshua Yap's current disclosures
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Synonyms:
- Psammoma body
Psammoma bodies are round microscopic calcific collections. It is a form of dystrophic calcification. Necrotic cells form the focus for surrounding calcific deposition. They have a lamellated concentric calcified structure, sometimes large enough to be seen on CT.
Psammoma bodies are found in a diverse group of tumors which include:
melanotic schwannoma (psammomatous variety) 3
History and etymology
The term is derived from the Ancient Greek psámmos meaning "sand" and ōma meaning "tumor", hence "sand tumor" 4.
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References
- 1. Nakayama H, Okumichi T, Nakashima S et-al. Papillary adenocarcinoma of the sigmoid colon associated with psammoma bodies and hyaline globules: report of a case. Jpn. J. Clin. Oncol. 1997;27 (3): 193-6. doi:10.1093/jjco/27.3.193 - Pubmed citation
- 2. Van mieghem IM, Gryspeerdt S, Baekelandt M et-al. Papillary serous adenocarcinoma of the endometrium: CT-pathologic correlation. AJR Am J Roentgenol. 2004;182 (6): 1534-6. AJR Am J Roentgenol (full text) - Pubmed citation
- 3. Shields LB, Glassman SD, Raque GH, Shields CB. Malignant psammomatous melanotic schwannoma of the spine: A component of Carney complex. Surgical neurology international. 2: 136. doi:10.4103/2152-7806.85609 - Pubmed
- 4. Sun T, Pitman M, Torous V. Determining the Significance of Psammoma Bodies in Pelvic Washings: A 10‐year Retrospective Review. Cancer Cytopathol. 2020;129(1):83-9. doi:10.1002/cncy.22346 - Pubmed
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Related articles: Histology
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blood
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blood
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histological stains
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- reticulin stain
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- Sudan stains
- toluidine blue stain
- van Gieson stain
- Ziehl-Neelsen stain
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