A ferruginous body is a histological finding in interstitial lung disease that is a result inorganic dust inhalation.
Macrophage ingestion of the inorganic fiber results in a fibrotic reaction with encasement of the fiber in iron-rich material that is derived from proteins such as ferritin and hemosiderin.
Where asbestos is confirmed as the fiber in the nidus of the body, it is termed an asbestos body.
- 1. Churg AM, Warnock ML. Asbestos and other ferruginous bodies: their formation and clinical significance. Am. J. Pathol. 1981;102 (3): 447-56. - Free text at pubmed - Pubmed citation