WHO classification of odontogenic and maxillofacial bone tumors

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~~2005~~2017 WHO histological classification of odontogenic and maxillofacial bone tumours

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~~The~~ ~~2005~~2017 WHO histological classification of odontogenic and maxillofacial bone tumours lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus. ~~At the time of writing (2016), it is still the most widely used classification system although a new revision is due to come up in 2017.~~

Classification

Malignant odontogenic tumours

odontogenic carcinomas
- ~~malignant ameloblastoma~~
- ameloblastic carcinoma~~: primary type~~
- ~~ameloblastic carcinoma: secondary type (dedifferentiated), intraosseous~~
- ~~ameloblastic carcinoma: secondary type (dedifferentiated), peripheral~~
- ~~primary intraosseous squamous cell carcinoma: solid type~~
- primary intraosseous ~~squamous cell carcinoma derived from keratocystic~~carcinoma, not otherwise specified
- sclerosing odontogenic ~~tumour~~carcinoma
- ~~primary intraosseous squamous cell carcinoma derived from an odontogenic cyst~~
- clear cell ~~odontogenic~~ondotogenic carcinoma
- ghost cell odontogenic carcinoma
odontogenic carcinosarcoma

odontogenic sarcomas

~~ameloblastic fibrosarcoma~~ ~~(ameloblastic sarcoma)~~
~~ameloblastic fibrodentinosarcoma~~ ~~and~~ ~~fibro-odontosarcoma~~

Benign odontogenic tumours

~~odontogenic epithelium mature, fibrous stroma without~~benign epithelial odontogenic ~~ectomesenchyme~~tumours
- ameloblastoma~~: solid/multicystic~~
  - ameloblastoma, unicystic type
  - ameloblastoma:, extraosseous/peripheral type
  - metastasising ameloblastoma~~: desmoplastic type~~
  ~~ameloblastoma: unicystic type~~
- squamous odontogenic tumour
- calcifying epithelial odontogenic tumour ~~(Pindborg tumour)~~
- adenomatoid ~~odontogenic tumour~~
- ~~keratocystic~~ odontogenic tumour
~~odontogenic epithelium with~~benign mixed epithelial and mesenchymal odontogenic ~~ectomesenchyme, with or without hard tissue formation~~tumours
- ameloblastic fibroma
- ~~ameloblastic fibrodentinoma~~ ~~(dentinoma)~~primordial odontogenic tumour
- odontoma
- ~~odontoma~~
  - ~~odontoma: complex type~~
  - ~~odontoma: compound type~~
- ~~odontoameloblastoma~~
- ~~calcifying cystic odontogenic cyst~~
- dentinogenic ghost cell tumour
~~mesenchyme and/or~~benign mesenchymal odontogenic ~~ectomesenchyme with or without odontogenic epithelium~~tumours
- odontogenic fibroma
- odontogenic myxoma ~~/ myxofibroma~~/myxofibroma
- cementoblastoma
- cemento -ossifying fibroma

Odontogenic cyst

odontogenic cysts of inflammatory origin
- radicular cyst
- inflammatory collateral cysts
odontogenic and non-odontogenic developmental cysts
- dentigerous cyst
- odontogenic keratocyst
- lateral periodontal cyst and botryoid odontogenic cyst
- gingival cysts
- glandular odontogenic cyst
- calcifying odontogenic cyst
- orthokeratinized odontogenic cyst
- nasopalatine duct cyst

Bone-relatedMalignant maxoillofacial bone and cartilage tumors

Benign maxoillofacial bone and cartilage tumors

Fibro-osseous and osteochondromatous lesions

ossifying ~~fibromas~~ (~~cemento-ossifying~~ fibroma)
familial gigantiform cementoma
fibrous dysplasia
~~osseous dysplasias~~
- cemento-osseous dysplasia
  - ~~periapical cemental dysplasia~~
  - osteochondroma
  Giant cell lesions and simple bone cyst
central giant cell granuloma
peripheral ~~central~~ giant cell ~~lesion (granuloma)~~granuloma
cherubism
aneurysmal bone cyst
simple bone cyst

Other tumoursHematolymphoid tumors

solitary plasmacytoma of ~~infancy~~bone

-<p>The <strong>2005 WHO histological classification of odontogenic tumours</strong> lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus. At the time of writing (2016), it is still the most widely used classification system although a new revision is due to come up in 2017. </p><h4>Classification</h4><h5>Malignant tumours</h5><ul>
+<p><strong>2017 WHO histological classification of odontogenic and maxillofacial bone tumours</strong> lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus.</p><h4>Classification</h4><h5>Malignant odontogenic tumours</h5><ul>
~~-<li><a href="/articles/malignant-ameloblastoma">malignant ameloblastoma</a></li>~~
~~-<li>~~
~~-<a href="/articles/ameloblastic-carcinoma">ameloblastic carcinoma</a>: primary type</li>~~
~~-<li>ameloblastic carcinoma: secondary type (dedifferentiated), intraosseous</li>~~
~~-<li>ameloblastic carcinoma: secondary type (dedifferentiated), peripheral</li>~~
~~-<li>~~
~~-<a href="/articles/primary-intraosseous-carcinoma">primary intraosseous squamous cell carcinoma</a>: solid type</li>~~
~~-<li>primary intraosseous squamous cell carcinoma derived from keratocystic odontogenic tumour</li>~~
~~-<li>primary intraosseous squamous cell carcinoma derived from an odontogenic cyst </li>~~
~~-<li><a href="/articles/clear-cell-odontogenic-carcinoma">clear cell odontogenic carcinoma</a></li>~~
~~-<li><a href="/articles/ghost-cell-odontogenic-carcinoma">ghost cell odontogenic carcinoma</a></li>~~
+<li>ameloblastic carcinoma</li>
+<li>primary intraosseous carcinoma, not otherwise specified</li>
+<li>sclerosing odontogenic carcinoma</li>
+<li>clear cell ondotogenic carcinoma</li>
+<li>ghost cell odontogenic carcinoma</li>
+<li>odontogenic carcinosarcoma</li>
+<li>odontogenic sarcomas</li>
+</ul><h5>Benign odontogenic tumours</h5><ul>
~~-<strong>odontogenic sarcomas</strong><ul>~~
~~-<li>~~
~~-<a href="/articles/ameloblastic-fibro-sarcoma">ameloblastic fibrosarcoma</a> (ameloblastic sarcoma)</li>~~
+<strong>benign epithelial odontogenic tumours</strong><ul>
~~-<a href="/articles/ameloblastic-fibro-dentinosarcoma">ameloblastic fibrodentinosarcoma</a> and <a href="/articles/ameloblastic-fibro-odontosarcoma">fibro-odontosarcoma</a>~~
+<a href="/articles/ameloblastoma">ameloblastoma</a><ul>
+<li>ameloblastoma, unicystic type</li>
+<li>ameloblastoma, extraosseous/peripheral type</li>
+<li>metastasising ameloblastoma</li>
+</ul>
+<li><a href="/articles/squamous-odontogenic-tumour">squamous odontogenic tumour</a></li>
+<li><a href="/articles/calcifying-epithelial-odontogenic-tumour">calcifying epithelial odontogenic tumour</a></li>
+<li><a href="/articles/adenomatoid-odontogenic-tumour">adenomatoid odontogenic tumour</a></li>
~~-</ul><h5>Benign</h5><ul>~~
~~-<li>~~
~~-<strong>odontogenic epithelium mature, fibrous stroma without odontogenic ectomesenchyme</strong><ul>~~
~~-<a href="/articles/ameloblastoma">ameloblastoma</a>: solid/multicystic type</li>~~
~~-<li>~~
~~-<a href="/articles/ameloblastoma">ameloblastoma</a>: extraosseous/peripheral type</li>~~
~~-<li>~~
~~-<a href="/articles/ameloblastoma">ameloblastoma</a>: desmoplastic type</li>~~
~~-<li>~~
~~-<a href="/articles/ameloblastoma">ameloblastoma</a>: unicystic type</li>~~
~~-<li><a href="/articles/squamous-odontogenic-tumour">squamous odontogenic tumour </a></li>~~
~~-<li>~~
~~-<a href="/articles/calcifying-epithelial-odontogenic-tumour">calcifying epithelial odontogenic tumour</a> (Pindborg tumour)</li>~~
~~-<li><a href="/articles/adenomatoid-odontogenic-tumour">adenomatoid odontogenic tumour</a></li>~~
~~-<li><a href="/articles/odontogenic-keratocyst">keratocystic odontogenic tumour</a></li>~~
+<strong>benign mixed epithelial and mesenchymal odontogenic tumours</strong><ul>
+<li><a href="/articles/ameloblastic-fibroma">ameloblastic fibroma</a></li>
+<li>primordial odontogenic tumour</li>
+<li><a href="/articles/odontoma">odontoma</a></li>
+<li>dentinogenic ghost cell tumour</li>
~~-<strong>odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation</strong><ul>~~
~~-<li><a href="/articles/ameloblastic-fibroma">ameloblastic fibroma </a></li>~~
+<strong>benign mesenchymal odontogenic tumours</strong><ul>
+<li>odontogenic fibroma</li>
~~-<a href="/articles/ameloblastic-fibrodentinoma">ameloblastic fibrodentinoma</a> (dentinoma)</li>~~
~~-<li><a href="/articles/ameloblastic-fibro-odontoma">ameloblastic fibro-odontoma</a></li>~~
+<a href="/articles/odontogenic-myxoma">odontogenic myxoma</a>/myxofibroma</li>
+<li><a href="/articles/cementoblastoma">cementoblastoma</a></li>
~~-<a href="/articles/odontoma">odontoma</a><ul>~~
~~-<li>odontoma: complex type</li>~~
~~-<li>odontoma: compound type</li>~~
~~-</ul>~~
+<a href="/articles/cemento-ossifying-fibroma">cemento</a><a href="/articles/cemento-ossifying-fibroma">-ossifying fibroma</a>
~~-<li><a href="/articles/odontoameloblastoma">odontoameloblastoma</a></li>~~
~~-<li><a href="/articles/calcifying-odontogenic-cyst">calcifying cystic odontogenic cyst</a></li>~~
~~-<li><a href="/articles/dentinogenic-ghost-cell-tumour">dentinogenic ghost cell tumour</a></li>~~
+</ul><h5>Odontogenic cyst</h5><ul>
~~-<strong>mesenchyme and/or odontogenic ectomesenchyme with or without odontogenic epithelium</strong><ul>~~
~~-<li><a href="/articles/odontogenic-fibroma">odontogenic fibroma</a></li>~~
~~-<li>~~
~~-<a href="/articles/odontogenic-myxoma">odontogenic myxoma</a> / myxofibroma</li>~~
~~-<li><a href="/articles/cementoblastoma">cementoblastoma</a></li>~~
+<strong>odontogenic cysts of inflammatory origin</strong><ul>
+<li><a href="/articles/periapical-cyst">radicular cyst</a></li>
+<li>inflammatory collateral cysts</li>
~~-</ul><h5>Bone-related lesions</h5><ul>~~
~~-<li>~~
~~-<a href="/articles/cemento-ossifying-fibroma">ossifying fibromas</a> (<a href="/articles/cemento-ossifying-fibroma">cemento-ossifying fibroma</a>)</li>~~
~~-<li><a href="/articles/fibrous-dysplasia">fibrous dysplasia</a></li>~~
~~-<a href="/articles/osseous-dysplasias">osseous dysplasias</a><ul><li>~~
~~-<a href="/articles/cemento-osseous-dysplasia-1">cemento-osseous dysplasia</a><ul>~~
~~-<li><a href="/articles/periapical-cemental-dysplasia">periapical cemental dysplasia</a></li>~~
~~-<li><a href="/articles/focal-cemento-osseous-dysplasia">focal cemento-osseous dysplasia</a></li>~~
~~-<li><a href="/articles/florid-cemento-osseous-dysplasia-1">florid cemento-osseous dysplasia</a></li>~~
+<strong>odontogenic and non-odontogenic developmental cysts</strong><ul>
+<li><a href="/articles/dentigerous-cyst">dentigerous cyst</a></li>
+<li><a href="/articles/odontogenic-keratocyst">odontogenic keratocyst</a></li>
+<li>lateral periodontal cyst and botryoid odontogenic cyst</li>
+<li>gingival cysts</li>
+<li>glandular odontogenic cyst</li>
+<li><a href="/articles/calcifying-odontogenic-cyst">calcifying odontogenic cyst</a></li>
+<li>orthokeratinized odontogenic cyst</li>
+<li><a href="/articles/incisive-canal-cyst">nasopalatine duct cyst</a></li>
~~-</li></ul>~~
~~-<li><a href="/articles/central-giant-cell-lesions-granuloma">central giant cell lesion (granuloma)</a></li>~~
+</ul><h5>Malignant maxoillofacial bone and cartilage tumors </h5><ul>
+<li><a href="/articles/chondrosarcoma">chondrosarcoma</a></li>
+<li><a href="/articles/mesenchymal-chondrosarcoma">mesenchymal chondrosarcoma</a></li>
+<li><a href="/articles/osteosarcoma">osteosarcoma</a></li>
+</ul><h5>Benign maxoillofacial bone and cartilage tumors</h5><ul>
+<li><a href="/articles/enchondroma">chondroma</a></li>
+<li><a href="/articles/osteoma">osteoma</a></li>
+<li><a href="/articles/melanotic-neuroectodermal-tumour-of-infancy">melanotic neuroectodermal tumour of infancy</a></li>
+<li><a href="/articles/chondroblastoma">chondroblastoma</a></li>
+<li><a href="/articles/chondromyxoid-fibroma">chondromyxoid fibroma</a></li>
+<li><a href="/articles/osteoid-osteoma">osteoid osteoma</a></li>
+<li><a href="/articles/osteoblastoma">osteoblastoma</a></li>
+<li><a href="/articles/desmoplastic-fibroma">desmoplastic fibroma</a></li>
+</ul><h5>Fibro-osseous and osteochondromatous lesions</h5><ul>
+<li><a href="/articles/ossifying-fibroma">ossifying fibroma</a></li>
+<li>familial gigantiform <a href="/articles/cementoblastoma">cementoma</a>
+</li>
+<li><a href="/articles/craniofacial-fibrous-dysplasia">fibrous dysplasia</a></li>
+<li>
+<a href="/articles/cemento-osseous-dysplasia-1">cemento</a><a href="/articles/cemento-osseous-dysplasia-1">-osseous dysplasia</a>
+</li>
+<li><a href="/articles/osteochondroma">osteochondroma</a></li>
+</ul><h5>Giant cell lesions and simple bone cyst </h5><ul>
+<li>central <a href="/articles/central-giant-cell-lesions-granuloma">giant cell granuloma</a>
+</li>
+<li>peripheral <a href="/articles/central-giant-cell-lesions-granuloma">giant cell granuloma</a>
+</li>
~~-</ul><h5>Other tumours</h5><ul><li><a href="/articles/melanotic-neuroectodermal-tumour-of-infancy">melanotic neuroectodermal tumour of infancy</a></li></ul>~~
+</ul><h5>Hematolymphoid tumors</h5><ul><li><a href="/articles/solitary-bone-plasmacytoma-1">solitary plasmacytoma of bone</a></li></ul>

References changed:

1. Adel K. El-Naggar, John K. C. Chan, Jennifer R. Grandis et al. WHO Classification of Head and Neck Tumours. (2017) ISBN: 9789283224389 - <a href="http://books.google.com/books?vid=ISBN9789283224389">Google Books</a>
1. Dunfee BL, Sakai O, Pistey R et-al. Radiologic and Pathologic Characteristics of Benign and Malignant Lesions of the Mandible1. Radiographics. 2006;26 (6): 1751-1768. <a href="http://radiographics.rsna.org/content/26/6/1751.full">Radiographics (full text)</a> - <a href="http://dx.doi.org/10.1148/rg.266055189">doi:10.1148/rg.266055189</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/17102048">Pubmed citation</a><span class="ref_v3"></span>
2. Kramer IRH, Pindborg JJ, Shear M. Histological typing of odontogenic tumours. Springer-Verlag. ISBN:038754142X. <a href="http://books.google.com/books?vid=ISBN038754142X">Read it at Google Books</a> - <a href="http://www.amazon.com/gp/product/038754142X">Find it at Amazon</a><span class="auto"></span>
3. Pathology And Genetics of Tumours of the Head And Neck. World Health Organization. ISBN:9283224175. <a href="http://books.google.com/books?vid=ISBN9283224175">Read it at Google Books</a> - <a href="http://www.amazon.com/gp/product/9283224175">Find it at Amazon</a><span class="auto"></span>

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odontogenic tumors.
odontogenic cysts
maxoillofacial bone tumors

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