Hampton hump of pulmonary embolus

Case contributed by Austin Donnelly
Diagnosis almost certain

Presentation

Left sided chest pain and shortness of breath.

Patient Data

Age: 60 years
Gender: Male

Normal cardiomediastinal contour.

Wedge-shaped airspace opacification at the left base.

Differential includes infection, pulmonary infarct (Hampton hump) or pulmonary hemorrhage.

The patient proceeded to CT pulmonary angiography.

CT pulmonary angiogram demonstrates filling defects in segmental and subsegmental arteries within the left hemithorax in keeping with pulmonary emboli. Wedge-shaped juxta pleural opacity in the distribution of the segmental pulmonary embolus in the left upper lobe in keeping with lung infarct.

Case Discussion

60 year old gentleman with a 1-day history of left-sided pleuritic chest pain. Abdominal surgery 5 weeks prior and subsequent decreased mobility.

Attended the emergency department (ED) and was treated expectantly with therapeutic enoxaparin and managed on an ambulatory pathway for suspected pulmonary embolism (PE).

While plain radiography is by no means considered the gold standard in the diagnosis of PE, there are a number of will recognized plain radiographic signs that have been described:

  • Hampton hump - peripheral, wedge-shaped air space opacity usually in the lower zones. To be more precise, Hampton hump implies pulmonary infarct rather than pulmonary embolism. 
  • Westermark sign - regional oligemia in the pulmonary segment supplied by the affected PE. 
  • Fleischner sign - Enlarged pulmonary artery. Can be seen in PE and pulmonary hypertension.

The sensitivity and specificity of these signs are not great enough to allow confident diagnosis, however, and in the appropriate clinical setting, further investigation CT pulmonary angiogram (CTPA) or ventilation-perfusion (V/Q scan) is warranted. 

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.