Hyperfunctioning autonomous thyroid nodule

Case contributed by Nathan McOrist
Diagnosis almost certain

Presentation

Patient presented with subclinical hyperthyroidism for assessment.

Patient Data

Age: 65 years
Gender: Female

Thyroid

ultrasound

The right lobe of the thyroid gland is enlarged measuring 21 x 23 x 48 mm.

Most of the right lobe of the thyroid contains a large, mixed echogenicity, spongiform nodule measuring 20 x 20 x 32 mm. There is evidence of some internal vascularity but within normal limits.

There is also a small nodule within the left upper lobe of the thyroid gland measuring 11 x 7 mm.

Technetium pertechnetate scan

Nuclear medicine

The thyroid gland is entirely supra-sternal with the right lobe appearing enlarged, the left lobe being normal.

There is a single homogenous focus of increased uptake within the left mid-upper lobe of the right thyroid in comparison to the background.

Case Discussion

Both the ultrasound and nuclear medicine scan point towards a diagnosis of a hyperfunctioning autonomous nodule ("hot" nodule).

If multiple of these nodules are seen, then a diagnosis of multinodular goiter is more likely but in the presence of a single hyperfunctioning nodule, an autonomous functioning nodule diagnosis is favored.

It is worth noting that almost all of hot nodules (>99%) are of benign pathology so often do not require biopsy 1.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.