Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

92 results found
Article

Acute abdominal pain

Acute abdominal pain is a common acute presentation in clinical practice. It encompasses a very broad range of possible etiologies and diagnoses, and imaging is routinely employed as the primary investigative tool in its modern management. Terminology A subgroup of patients with acute abdomina...
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Acute airspace opacification with lymphadenopathy (differential)

Acute airspace opacification with lymphadenopathy is a subset of the differential diagnosis for generalized airspace opacification and includes: post-obstructive causes (usually chronic, but 'new' changes can occur) primary lung cancer pulmonary metastases lymphoma/leukemia infection prim...
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Acute myeloid leukemia

Acute myeloid leukemia (AML), also referred to as acute myelogenous leukemia, is a hematological malignancy characterized by the abnormal clonal proliferation of immature myeloid precursors (myeloblasts) or poorly differentiated cells of the hematopoietic system. It primary infiltrates the bone ...
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Adrenal calcification

Adrenal calcification is not a rare finding in healthy asymptomatic people and is usually the result of previous hemorrhage or tuberculosis. Addison disease patients only occasionally develop calcification.  Pathology Etiology Hemorrhage sepsis: Waterhouse-Friderichsen syndrome blunt abdomi...
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Adult cervical lymphadenopathy (differential)

Cervical lymphadenopathy in an adult can result from a vast number of conditions. They include: malignancy metastases  from head and neck tumors lymphoma other neoplastic lesions Castleman disease Kaposi sarcoma infection bacterial infection viral infection Epstein-Barr virus herpes ...
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Apple core sign (colon)

The apple core sign, also known as the napkin ring sign (bowel), is most frequently associated with constriction of the lumen of the colon by a stenosing annular colorectal carcinoma. Differential diagnosis The appearance of the apple-core lesion of the colon also can be caused by other diseas...
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Architectural distortion in mammography

Architectural distortion is a mammographic descriptive term in breast imaging. It may be visualized as tethering or indentation of breast tissue. Pathology Architectural distortion per se is not a mass. It is often due to a desmoplastic reaction in which there is focal disruption of the normal...
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Asymmetrical density in mammography

Asymmetrical mammographic density is a mammographic morphological descriptor. It is given when there is increased density in one of the breasts, on either one or both standard mammographic views but without evidence of a discrete mass. The criteria for an asymmetry may include borders of the ti...
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Bat wing opacities (lungs)

Bat's wing or butterfly pulmonary opacities refer to a pattern of bilateral perihilar shadowing. It is classically described on a frontal chest radiograph but can also refer to appearances on chest CT 3-4. Differential diagnosis Bat's wing pulmonary opacities can be caused by: pulmonary edema...
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Benign metastasizing tumors

There are a number of benign metastasizing tumors: benign metastasizing meningioma 1,2 benign metastasizing leiomyoma 3 primary adenoma of thyroid 4 giant cell tumor of bone 5
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Bilateral testicular lesions

Bilateral testicular lesions have a relatively limited differential diagnosis.  Differential diagnosis Neoplastic  lymphoblastic leukemia (acute or chronic) lymphoma (non-Hodgkin's) primary testicular lymphoma is rare but the testes are often the site of lymphoma/leukemia recurrence due to ...
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Bone lesions with sequestrum

There are several bony lesions that can involve or depict a sequestrum. They include: Common brodie abscess: osteomyelitis Less common eosinophilic granuloma certain soft tissue tumors (with bony extension)  malignant fibrous histiocytoma lymphoma metastasis (especially from breast car...
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Brachytherapy

Brachytherapy, also known as sealed source radiotherapy or endocurietherapy, is a form of radiotherapy where a radioactive source is placed, under the guidance of imaging, within or next to the area requiring treatment. Brachytherapy has been used to treat: prostate cancer breast cancer (ofte...
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Bulging duodenal papilla

Major duodenal papilla is a conic or cylindric protuberance at the medial aspect of the descending or horizontal duodenum at the site of the sphincter of Oddi. It is finding on small bowel follow-though (and endoscopy) and has a relatively long differential. On cross sectional imaging, the unde...
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CA-125

CA-125 is a high-molecular-weight glycoprotein found on the surface of Mullerian and coelomic epithelial-derived cell types, and is the best known tumor marker for epithelial ovarian cancer 6. Importantly, it may also be elevated in several other conditions (see differential diagnosis section be...
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CA 19-9

CA 19-9 (carbohydrate antigen 19-9 or cancer antigen 19-9) is a serum antigen (monosialoganglioside) that has increased diagnostic use in the management of several malignancies, mainly of hepatopancreaticobiliary origin. It is non-specific, however, and can rise in both malignant and non-maligna...
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Calcified mediastinal lymph nodes (differential)

There are numerous causes of calcified mediastinal lymph nodes. Common causes include: infectious granulomatous diseases tuberculosis histoplasmosis sarcoidosis silicosis treated lymphoma Uncommon causes include: Pneumocystis jiroveci (PCP) pneumonia metastases thyroid carcinoma: papi...
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Cardiophrenic angle lesions

The cardiophrenic space is usually filled with fat. However, lesions originating above or lower to the diaphragm can present as cardiophrenic angle lesions. The more common lesions encountered include: pericardial fat pad pericardial cyst pericardial fat necrosis Morgagni's hernia lymphade...
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CEA

Serum CEA (carcinoembryonic antigen) is a cell-adhesive glycoprotein that was discovered in colorectal cancer in 1965, and is hence one of the oldest and most used tumor markers. Its name derives from its normal expression in fetoembryonic liver, gut and pancreas tissue. Normal range of CEA is ...
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Cerebral ring enhancing lesions

The differential for peripheral or ring enhancing cerebral lesions includes: cerebral abscess tuberculoma neurocysticercosis metastasis glioblastoma subacute infarct/hemorrhage/contusion demyelination (incomplete ring) tumefactive demyelinating lesion (incomplete ring) radiation necrosi...
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Childhood malignancies

Unfortunately the pediatric population is susceptible to malignancies. The most common entities, in overall order of frequency, are 1-4: leukemia/lymphoma: ~35% * acute lymphoblastic leukemia: 23% Hodgkin disease: 5% acute myelogenous leukemia: 4% central nervous system malignancies: ~20% ...
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Clavicle tumors

Clavicle tumors may be malignant or benign. Malignant metastases prostate breast cervix ovary urinary bladder carcinoid osteosarcoma osteosarcoma lymphoma primary metastatic Benign osteoma: uncommon, sclerotic, hamartomatous surface lesion enchondroma: rare, geographic, intramedu...
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Cystic lesions of the pancreas (differential)

The differential for cystic lesions of the pancreas includes: unilocular pancreatic pseudocyst intraductal papillary mucinous neoplasm (IPMN) serous cystadenoma uncommonly uni/macrolocular simple pancreatic cyst pancreatic cysts occur in association with  von Hippel Lindau syndrome autos...
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Cystic (necrotic) lymph nodes

Cystic or necrotic appearing lymph nodes can be caused by a number of infectious, inflammatory or malignant conditions: Systemic squamous cell carcinoma metastases treated lymphoma leukemia plasmacytoid T-cell leukemia acute myeloid leukemia viral lymphadenitis herpes simplex lymphadenit...
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Cystic pulmonary metastases

Cystic pulmonary metastases are atypical morphological form on pulmonary metastases where lesions manifest as distinct cystic lesions. It is slightly different from the term cavitating pulmonary metastases in that the lesions are extremely thin walled. Pathology It has been reported with many ...
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Differential for an anterosuperior mediastinal mass

An anterosuperior mediastinal mass can be caused by neoplastic and non-neoplastic pathology. As their name suggests, they are confined to the anterior mediastinum, that portion of the mediastinum anterior to the pericardium and below the level of the clavicles.  The differential diagnosis for a...
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Diffusely increased bone marrow FDG uptake

A diffuse homogeneous bone marrow FDG uptake usually reflects hyperplastic bone marrow which can be seen in the following conditions: therapy-related granulocyte colony stimulating factor (G-CSF) post-chemotherapy erythropoietin pathological process myelodysplastic syndromes beta thalasse...
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Endosteal scalloping

Endosteal scalloping refers to the focal resorption of the inner layer of the cortex (i.e. the endosteum) of bones, most typically long bones, due to slow-growing medullary lesions. It is important to note that although it is evidence of a slow non-infiltrative lesion, it does not equate to ben...
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Ewing sarcoma family of tumors

Ewing sarcoma family of tumors are a group of small round blue cell tumors that are closely histogenetically related, all demonstrating non-random t(11;22)(q24;q12) chromosome rearrangement resulting in the formation of the EWS-ETS fusion gene 1-3.  Terminology Although the literature is litte...
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Fetal cardiac tumors

Fetal cardiac tumors refer to primary cardiac tumors that can present in the in utero population.  Epidemiology Fetal cardiac tumors are rare; the prevalence, reported from autopsy studies of patients of all ages, varies from 0.0017-0.28 % 2. Pathology Known cardiac tumor types that present ...
Article

Focal gas collection in right upper quadrant (differential)

Focal gas collection in right upper quadrant on plain radiographs can occur from a number of pathologies. Things to consider are: enterobiliary fistula: common types include cholecystoduodenal fistula and cholecystocolic fistula. It may occur with: gallstone ileus (being most common) 3 perfor...
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Generalized osteopenia

Generalized osteopenia refers to osteopenia diffusely affecting the bones. Differential diagnosis The differential diagnosis is wide and includes: osteoporosis: decreased osteoid production osteomalacia: undermineralisation of osteoid hyperparathyroidism multiple myeloma diffuse metastase...
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Hepatosplenomegaly

Hepatosplenomegaly is simply the simultaneous presence of a pathologically-enlarged liver (hepatomegaly) and spleen (splenomegaly). Pathology Etiology Infection Many, many infections can produce a mild concurrent enlargement of the liver and spleen. This list is by no means exhaustive! vira...
Article

HIV associated neoplasms

HIV-associated neoplasms are numerous and can be broadly divided into two groups: AIDS-defining malignancies associated but not AIDS defining malignancies AIDS-defining malignancies The development of these malignancies in HIV affected individuals generally implies progression to AIDS 4: Ka...
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Hypertrophic osteoarthropathy

Hypertrophic osteoarthropathy is a syndrome characterized by periosteal reaction of the long bones without underlying bone lesion. There are a broad range of manifestations, although typically there is symmetrical involvement of the appendicular skeleton. Accompanying abnormal soft tissue prolif...
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Hypervascular metastases

There are several tumors which are noted to cause hypervascular metastases. The list of differential diagnoses includes: renal cell carcinoma (RCC) breast cancer: homogeneously hypervascular liver metastases from breast are considered rare 3 lung cancer neuroendocrine tumors carcinoid tumor...
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Hypothalamic lesions

Hypothalamic lesions are numerous representing some entities that are unique to the hypothalamus, as well as many lesions that can be seen elsewhere within the brain. Additionally, due to its proximity to the optic chiasm, third ventricle and pituitary region, many lesions of these locations can...
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Intramedullary spinal metastasis

Intramedullary spinal metastases are rare, occurring in ~1% of autopsied cancer patients, and are less common than leptomeningeal metastases. Intramedullary lesions may result from: growth along the Virchow-Robin spaces haematogenous dissemination direct extension from leptomeninges Epidemi...
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Intraventricular neoplasms and lesions

Intraventricular neoplasms are rare and arise from periventricular structures such as the walls of the ventricular system, the septum pellucidum and the choroid plexus. Many tumor types arise from, or can bulge into the ventricular system, although there are certain lesions that are relatively r...
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Leptomeningeal enhancement

Leptomeningeal enhancement refers to a diffuse or focal gyriform or serpentine enhancement that can be seen in the following conditions: Diffuse meningitis pyogenic meningitis viral meningitis tuberculous meningitis (can also be focal) CNS cryptococcal infection coccidioidal meningitis (c...
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Leukemia

Leukemia is a hematological neoplasm characterized by the overproduction of immature (blasts) or abnormally differentiated cells of the hematopoietic system in the bone marrow that often, but not always, extends into the peripheral blood.  This article aims to provide an overview of leukemia as...
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Lipoma vs well-differentiated liposarcoma

There a number of features that can help distinguish between lipoma and well-differentiated liposarcoma. This article relates to superficial well-differentiated liposarcomas that typically occur in the extremities, and not retroperitoneal liposarcoma. Epidemiology Demographic factors that favo...
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Liver tumors

Liver tumors, like tumors of any organ, can be classified as primary or secondary. Metastases Liver metastases are by far the most common hepatic malignancy, with many of the most common primaries readily seeding to the liver. This is especially the case with gastrointestinal tract tumors, due...
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Male breast disease

Male breast disease includes a wide spectrum of conditions. Many conditions and entities that affect the female breast may also affect the male breast.  Pathology Malignant male breast cancer lymphoma dermatofibrosarcoma Benign gynecomastia pseudogynecomastia: fat deposition within the b...
Article

Mandibular lesions

Mandibular lesions are myriad and common. The presence of teeth results in lesions that are specific to the mandible (and maxilla) and a useful classification that defines them as odontogenic or non-odontogenic. While it may often not be possible to make a diagnosis on imaging alone, this classi...
Article

Mediastinal lymph node enlargement

Mediastinal lymph node enlargement can occur from a wide range of pathologies. It may occur on its own or in association with other lung pathology. Terminology Although mediastinal lymphadenopathy is used interchangeably - by some - with "mediastinal lymph node enlargement", they are not synon...
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Multiple cystic neck lesions (differential)

The differential diagnosis for multiple cystic neck lesions is different to that for a solitary cystic neck mass. Differential diagnosis Cystic neck lesions are seen in: necrotic metastatic SCC nodes: older patient, M>F papillary thyroid carcinoma metastases: usually a younger patient, F>M ...
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Non-seminomatous germ cell tumors

Non-seminomatous germ cell tumors (NSGCT) are one of the main groups of germ cell tumors (the other being seminoma). Although they are made up of distinct histological entities, in general, they have similar radiographic appearances. They can, however, be found widely in the body, with variable ...
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Ocular pathology

Ocular pathology covers a wide range of conditions and therefore represents the cause of a wide range of symptoms, signs and radiographic features. Ocular metastases account for over 80% of all ocular pathology. With regard to the remainder of ocular lesions, the primary differentiating factor ...
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Oligometastases

Oligometastases refers to distant disease that is limited in number and distribution, Niibe et al. defined this as ≤5 metastatic/recurrent lesions with control of the primary lesion 1,2. These metastases can be treated with local measures (surgery, radiation therapy, etc.) with the aim of increa...
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Omental cake

Omental cake refers to infiltration of the omental fat by material of soft-tissue density. The appearances refer to the contiguous omental mass simulating the top of a cake. Masses on the peritoneal surfaces and malignant ascites may also be present.  Pathology The most common cause is metasta...
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Optic nerve enlargement

Enlargement of the optic nerves is uncommon and has a surprisingly broad differential: optic nerve glioma optic nerve meningioma orbital pseudotumour optic neuritis sarcoidosis leukemia orbital lymphoma metastases perioptic hemorrhage Erdheim-Chester disease juvenile xanthogranuloma ...
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Pediatric renal tumors and masses

Pediatric renal tumors and masses are another group of diseases (just like cystic renal diseases in both the adult and child) that are bewildering in their number, nomenclature and overlapping findings. Commoner lesions Wilms tumor: common in older children 1-8 years old nephroblastomatosis: ...
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Pancreatic calcifications

Pancreatic calcifications can arise from many etiologies. Punctate intraductal calcifications chronic pancreatitis alcoholic pancreatitis (20-40%) 2  intraductal, numerous, small, irregular preponderant cause of diffuse pancreatic intraductal calcification gallstone pancreatitis (2%) 2 ​m...
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Pancreatic neoplasms

There are numerous primary pancreatic neoplasms, in part due to the mixed endocrine and exocrine components. Classification Classification based on function exocrine: ~99% of all primary pancreatic neoplasms pancreatic ductal adenocarcinoma ~90-95% cystic neoplasm intraductal papillary muc...
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Parotid enlargement

Parotid enlargement (also known as parotidomegaly) has a wide differential given the significant breadth of pathology that can affect the parotid gland. These can be separated by the standard surgical sieve approach into infective, inflammatory, immune, neoplastic, infiltrative, and congenital c...
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Patellar tumors

Patellar tumors are extremely rare. They can be either benign or malignant primary bone tumors, or metastases.  Epidemiology Patellar tumors represent just 0.1% of all primary bone tumors 1.  Clinical presentation Patients may present with anterior knee pain and/or a palpable mass 1,3. Path...
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Pedunculated intratracheal mass

A pedunculated intratracheal mass has a variety of differential diagnoses: benign tumor, e.g. hamartoma, chrondroma, lipoma hemangioma inspissated mucus metastasis to tracheal mucosa, e.g. renal cell carcinoma, melanoma polyp, e.g. inflammatory, antrochoanal papilloma post-intubation trac...
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Pelvic masses in females

Pelvic masses in females carry a broad differential diagnosis: benign adnexal cyst: 34% leiomyoma: 14% pelvic malignancy: 14% dermoid: 13% endometriosis: 10% pelvic inflammatory disease: 8% tubo-ovarian abscess hydrosalpinx pregnancy Extra-gynecological masses, e.g. colorectal carcinom...
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Peritoneal calcification

Peritoneal calcification is seen in a limited number of conditions that result in calcification of peritoneal structures. Therefore, the differential diagnosis is small: psammoma bodies in malignancy (most frequently cystadenocarcinoma of the ovary): fine sand-like calcification pseudomyxoma p...
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PET-CT indications

PET-CT is a combination of cross-sectional anatomic information provided by CT and the metabolic information provided by positron emission tomography (PET). PET is most commonly performed with 2-[F-18]fluoro-2-deoxy-D-glucose (FDG). Fluorine-18 (F-18) is an unstable radioisotope and has a half-...
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Pleural lymphoma

Pleural involvement with lymphoma can occur in two situations: primary pleural lymphoma primary effusion lymphoma secondary involvement of the pleura with lymphoma
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Post surgical breast scar

Post surgical breast scar is a benign complication that usually occurs following  surgical intervention to breast tissue. It can however be a strong and potentially very confusing mimicker of breast malignancy. Radiographic features Review of the patient's past history and previous mammography...
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Primary benign cardiac tumors

Primary benign cardiac tumors are much less common than secondary metastatic deposits. However they are more likely when a cardiac mass is seen outside of the setting of terminal metastatic disease. Tumors include 1-2: cardiac myxoma most common in adults accounts for ~50% of all primary beni...
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Primary malignancy of the nasopharynx

There are a number of primary malignancies of the nasopharynx: nasopharyngeal carcinoma (squamous cell carcinoma): 70% lymphoma (sinonasal lymphoma): 20% other nasopharyngeal papillary adenocarcinoma adenoid cystic carcinoma mucosal melanoma extramedullary plasmacytoma carcinosarcoma fi...
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Pseudocirrhosis

Pseudocirrhosis is a radiological term used to recapitulate imaging findings of cirrhosis, but occurring in the setting of hepatic metastases. It is most commonly reported following chemotherapeutic treatment of breast cancer metastases, although has also been reported before treatment, and with...
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Pulmonary metastases

Pulmonary metastases are common and the result of metastatic spread from a variety of primary tumors via blood or lymphatics. This article describes haematogenous pulmonary metastases with lymphangitis carcinomatosis discussed separately. Epidemiology The epidemiology will match that of the u...
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Pure ground glass nodules

Pure ground glass lung nodules are a subtype of ground glass lung nodules where there is no associated solid component. They have been shown to represent various pathologies such as 1,3 adenocarcinoma in situ of lung minimally-invasive adenocarcinoma of lung invasive adenocarcinoma of lung ...
Article

RASopathy

RASopathies are a class of developmental disorders caused by germline mutations in genes that encode for components or regulators of the Ras/mitogen-activated protein kinase (MAPK) pathway. Epidemiology As a group, RASopathies represent one of the most common malformation syndromes, with an in...
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Response evaluation criteria in solid tumors

Response evaluation criteria in solid tumors or RECIST refers to a set of published rules used to assess tumor burden in order to provide an objective assessment of response to therapy. They were initially introduced in 2000 and have undergone subsequent revision in 2009 (RECIST 1.1). For the ev...
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Salivary gland tumors

Salivary gland tumors are variable in location, origin, and malignant potential.  Pathology In general, the ratio of benign to malignant tumors is proportional to the gland size; i.e. the parotid gland tends to have benign neoplasms, the submandibular gland 50:50, and the sublingual glands and...
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Secondary organizing pneumonia

Secondary organizing pneumonia (SOP) refers to organizing pneumonia that can be attributed to a specific cause, in contrast to cryptogenic organizing pneumonia (COP). Pathology Etiology SOP can be attributed to the following causes 1: Prior infection bacteria atypical pneumonias (e.g. Legi...
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Smoking related lung disease

Smoking related lung diseases are the respiratory manifestations of disease that is related to smoking. Smoking affects the lungs in numerous ways, and can be classified under the following headings: smoking related interstitial lung diseases (SR-ILD) respiratory bronchiolitis (RB) respirator...
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Soft-tissue sarcoma

Soft-tissue sarcomas are a heterogeneous group of malignant tumors of mesenchymal origin (sarcoma) that originate from the soft tissues rather than bone. They are classified on the basis of tissue seen on histology. The commoner sarcomas in the adult and pediatric population are listed below. A...
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Solid and enhancing pituitary region mass

Solid lesions with enhancement is by far the most commonly encountered appearance of pituitary region masses. Differential diagnosis macroadenoma by far the most common entity typically enhances less vividly than other entities elevates the dura of the diaphragma sella (as the origin is wit...
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Solid periosteal reaction

Solid periosteal pattern is thought to evolve from single layer and multilayered periosteal reactions, forming a solid layer of new bone adjacent to the cortex. It can be seen in: osteoid osteoma osteomyelitis osteosarcoma chondrosarcoma fibrous dysplasia non-ossifying fibroma osteoblast...
Article

Solitary sclerotic bone lesion

The differential diagnosis of a solitary sclerotic bone lesion is heavily influenced by the age of the patient, and includes: sclerotic metastasis solitary either because no others are present or no others have been imaged enostosis (bone island) osteosarcoma calcifying enchondroma osteobl...
Article

Spinal metastases

Spinal metastases is a vague term which can be variably taken to refer to metastatic disease to any of the following: vertebral metastases (94%) may have epidural extension intradural extramedullary metastases (5%) intramedullary metastases (1%) Each of these are discussed separately. Below...
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Splenomegaly

Splenomegaly refers to enlargement of the spleen. The upper limit of normal adult splenic length is traditionally cited at 12 cm, but lengths upwards of 14 cm can be seen in normal, taller males 7. Massive splenomegaly is variably defined, including when the spleen is 5 standard deviations abov...
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Sunburst appearance (bone)

Sunburst appearance is a type of periosteal reaction giving the appearance of a sunburst secondary to an aggressive periostitis. It should not be confused with the sunburst sign of meningioma vascularity.  The sunburst appearance occurs when the lesion grows too fast and the periosteum does not...
Article

Superscan

Superscan is intense symmetric activity in the bones with diminished renal and soft tissue activity on a Tc99m diphosphonate bone scan. This appearance can result from a range of etiological factors: diffuse metastatic disease prostatic carcinoma breast cancer transitional cell carcinoma (T...
Article

Terminal ileitis (differential)

The differential diagnosis for a terminal ileitis is quite extensive, and includes: inflammatory bowel disease Crohn disease (most common) backwash ileitis due to ulcerative colitis infectious colitis Yersinia spp.  Yersinia enterocolitica Yersinia pseudotuberculosis Salmonella spp. ​Sa...
Article

Testicular cancer

Testicular cancers are the most common neoplasm in men between the ages of 20 and 34 years. Epidemiology Testicular cancer is uncommon, accounting for less than 1% of all internal organ malignancies 2. The demographics of affected individuals depends on the age of the histology of the tumor. ...
Article

Thyroid malignancies

Thyroid malignancies are most commonly primary thyroid cancers but can rarely be metastatic deposits. Pathology Classification Thyroid malignancies can be categorized into the following key subtypes: primary thyroid cancers ​papillary thyroid carcinoma: 60-80% of carcinomas follicular thyr...
Article

Tracheal masses

The differential for tracheal masses can be rather wide. For a single mass consider: metastasis  direct invasion from adjacent organ (lung, thyroid, esophagus and larynx) distant metastasis (e.g. melanoma, breast, renal and colon cancer)  primary neoplasms: squamous cell carcinoma: commone...
Article

Tuberculosis (intracranial manifestations)

Tuberculosis of the central nervous system can result from either haematogenous spread from distant systemic infection (e.g. pulmonary tuberculosis) or direct extension from local infection (e.g. tuberculous otomastoiditis). Intracranial manifestations of tuberculosis are protean and can affect...
Article

Tumors of the male urethra

Tumors of the male urethra are uncommon. They can be categorized both on the grounds of histology and location. Histology squamous cell carcinoma of the urethra: 80% urothelial/transitional cell carcinoma of the urethra: 15% (predominantly posterior urethra) adenocarcinoma of the urethra: 5%...
Article

Ultrasound appearances of liver metastases

Ultrasound appearance of liver metastases can have bewildering variation, and the presence of hepatic steatosis can affect the sonographic appearance of liver lesions. Radiographic features Ultrasound Patterns do exist between ultrasound appearance of the liver metastases and the likely prima...
Article

Unilateral axillary lymphadenopathy (differential)

Unilateral axillary lymphadenopathy while being more concerning than bilateral axillary lymphadenopathy can still arise from a various benign as well as malignant causes. Benign mastitis other regional infective causes tuberculosis ipsilateral arm infection, e.g. cellulitis silicone induce...
Article

Unilateral testicular lesions

The differential diagnosis for unilateral testicular lesions is wide-ranging.  Neoplastic Common seminoma (40-50% of testicular malignancies) non-seminomatous germ cell tumors: testicular teratoma testicular epidermoid (teratoma with ectodermal elements only) testicular choriocarcinoma t...
Article

Vertebra plana

Vertebra plana (pleural: vertebrae planae), also known as the pancake or silver dollar or coin-on-edge vertebra, is the term given when a vertebral body has lost almost its entire height anteriorly and posteriorly, representing a very advanced compression fracture. Pathology It can occur in a ...
Article

Vulval neoplasms

Vulval neoplasms are rare and mostly seen in elderly female patients. Squamous cell carcinoma (SCC) is the most common malignancy of the vulva and only 30% of them are associated with oncogenic human papillomaviruses (HPVs). Pathology Squamous neoplastic lesions  Premalignant  classic vulvar...

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