Articles

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746 results found
Article

Hemolytic anemia

Hemolytic anemia is a form of anemia where red blood cells are destroyed faster than they can be replaced. This may happen either intravascularly or extravascularly. Clinical presentation The patient presents with anemia and jaundice. Diagnosis is based on several laboratory parameters 1: ret...
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Nerve root enhancement

Nerve root enhancement is a phenomenon described on post-contrast MRI scans that can be observed in a number of situations. Common causes post-operative nerve root enhancement 6 arachnoiditis leptomeningeal metastases disseminated spinal leptomeningeal metastases neurolymphomatosis HIV va...
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Dural ectasia

Dural ectasia refers to ballooning or widening of the dural sac which can result in posterior vertebral scalloping and is associated with herniation of nerve root sleeves. Clinical presentation Patients with dural ectasia may present with low back pain or radicular pain in the buttocks or legs...
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Spinal metastasis

Spinal metastasis is a vague term that can be variably taken to refer to metastatic disease to any of the following: vertebral metastases (94%) may have epidural extension intradural extramedullary metastases (5%) intramedullary metastases (1%) Each of these are discussed separately. Below ...
Article

Perianal disease

Perianal disease, also known as anorectal disease, is the collective name given to a group of diseases that primarily affect the anal canal +/- rectum. The disease spectrum ranges from the typically benign, e.g. hemorrhoids, to the potentially more serious, e.g. perianal fistula 1-3. hemorrhoid...
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Splenic lesions and anomalies

There are a number of splenic lesions and anomalies: Gamuts hypervascular splenic lesions Congenital anomalies accessory spleen wandering spleen asplenia polysplenia bipartite spleen splenogonadal fusion retrorenal spleen Mass lesions Benign mass lesions splenic cyst splenic pseudo...
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Pneumatocele

Pneumatoceles are intrapulmonary gas-filled cystic spaces that can have a variety of sizes and appearances. They usually occur as a result of a pneumonia or in neonates are the result of a ventilator-induced lung injury. They should not be mistaken for a cavitating lung mass.  Epidemiology Alt...
Article

Pure ground glass nodules

Pure ground glass lung nodules (pGGN's) are a subtype of ground glass lung nodules where there is no associated solid component. Pathology Etiology Apart from inflammatory foci they have been shown to represent various pathologies such as 1,3 adenocarcinoma in situ of lung minimally-invasiv...
Article

Cardiac calcification

Cardiac calcification is a broad term for any calcification affecting the valves, coronary arteries, aortic root, endocardium, myocardium, and/or pericardium. Pathology Causes of cardiac calcification are: coronary artery disease (most common) coronary artery aneurysms, e.g. in Kawasaki dise...
Article

Terminal ileitis (differential)

The differential diagnosis for a terminal ileitis is quite extensive, and includes: inflammatory bowel disease Crohn disease (most common) backwash ileitis due to ulcerative colitis infectious colitis Yersinia spp.  Yersinia enterocolitica Yersinia pseudotuberculosis Salmonella spp. ​Sa...
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Reverse bat wing pulmonary opacities

Reverse bat wing pulmonary opacities refer to peripheral opacities of the lungs, sparing the perihilar region. It is a relatively unusual appearance with a fairly narrow differential 1: common chronic eosinophilic pneumonia 2,3 organizing pneumonia 3,5 rare pulmonary contusion: in the setti...
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Surgical sieve (mnemonic)

A surgical sieve is an approach to differential diagnosis that prompts the user to consider various types of pathologies systematically. A surgical sieve does not need to be a mnemonic 2, although many find it easier to remember it when a mnemonic is used. Various versions of this mnemonic exist...
Article

Pituitary region mass with intrinsic high T1 signal

Pituitary region masses with intrinsic high T1 signal, also referred to as suprasellar hotspots, are relatively frequently encountered, and the presence of high T1 signal narrows the differential somewhat.  Differential diagnosis The differential can be divided by the substance causing the T1 ...
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Shortening of the fourth/fifth metacarpals

Shortening of the fourth/fifth metacarpals (brachymetacarpia) and less commonly metatarsals (brachymetatarsia) is seen in a variety of apparently disparate conditions.  Pathology Etiology Common causes 2: idiopathic post-infective (e.g. osteomyelitis, yaws, tuberculosis dactylitis) pseudoh...
Article

Nontoxic megacolon

Nontoxic megacolon refers to colonic dilatation without mural abnormality and signs of colon toxicity. Although the definition of a megacolon has varied in the literature, most use the measurement of greater than 12 cm for the cecum, 8 cm for the ascending and transverse colon, and 6.5 cm for th...
Article

Cerebral cortical calcification

Cerebral cortical calcification or gyral calcification refers to curvilinear calcifications involving the cerebral cortex. Differential diagnosis vascular ischemic stroke sequelae arteriovenous malformation TORCH infection congenital cerebral toxoplasmosis congenital cytomegalovirus infec...
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Optic canal enlargement

Optic canal enlargement can be caused by numerous etiologies. Pathology The optic canal has an average transverse diameter of 3.6 ± 0.6 mm 1. The optic canal can be considered enlarged when it is >6.5 mm in transverse diameter 4. Etiology glioma of optic nerve meningioma of optic nerve shea...
Article

Lumbar epidural gas

Lumbar epidural gas is a rare phenomenon where gas locules are observed within the central canal of the lumbar spine. It can arise from a number of factors: due to regional degenerative disc disease with or without dorsal epidural disc migration: thought to be from gas leaking from the disc spa...
Article

Communicating hydrocephalus

Communicating hydrocephalus is a type of hydrocephalus where CSF is able to leave the ventricular system.  Terminology Communicating hydrocephalus is commonly used as the opposite of obstructive hydrocephalus, which leads to much unnecessary confusion, as most causes of communicating hydroceph...
Article

Urinary bladder wall thickening

Urinary bladder wall thickening is a common finding and its significance depends on whether the bladder is adequately distended. Radiographic features Ultrasound In both adults and children, the wall may be considered thickened on ultrasound if it measures 6: >3 mm when distended (>25% expec...

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